by Johns Hopkins University School of Medicine Image from a Johns Hopkins Medicine study showing PET scans from brains of people with and without late-life depression. The brains of patients with late-life depression show more yellow to red regions (scans on the left), indicating higher amyloid beta protein levels, and more blue regions (scans on the...
Tag: <span>amyloid-beta</span>
Study solves mystery of how amyloid beta forms in brain nerve cells
MASSACHUSETTS GENERAL HOSPITAL BOSTON – In a major breakthrough, researchers at Massachusetts General Hospital (MGH) have discovered how amyloid beta–the neurotoxin believed to be at the root of Alzheimer’s disease (AD)–forms in axons and related structures that connect neurons in the brain, where it causes the most damage. Their findings, published in Cell Reports, could serve as a...
Protein shapes matter in Alzheimer’s research
by Allison Mills, Michigan Technological University Sometimes proteins misfold. When that happens in the human brain, the pileup of misfolded proteins can lead to neurodegenerative diseases like Alzheimer’s, Parkinson’s and ALS. Proteins do not misbehave and misfold out of the blue. There is a delicate ecosystem of biochemical interactions and environments that usually let them...
Discovery: Scientists find for the first time how the eyes drain cellular waste and debris
by Delthia Ricks , Medical Xpress Just as the brain is a privileged organ, so too are the eyes. Often poetically called the windows to the soul, a unique set of studies has begun to regard the eyes in another way. Like the brain, the eyes lack the classic lymphatic vessels responsible for the circulation...
Could this medical breakthrough help cure Alzheimer’s? Scientists identify rogue proteins behind disease
Researchers at the National Institutes of Health have identified how the neurological conditions develop differently between patients The finding could revolutionise medical treatment and even lead to new drugs About 850,000 people are living with Alzheimer’s in the UK, a figure expected to to rise to a million by 2025 The treatment of Alzheimer’s Disease...