September 12, 2024 by Brain Chemistry Labs Neurally-derived extracellular vesicles extracted from a standard blood sample contain microRNA sequences used to diagnose ALS. Credit: Paul Cox.A highly accurate diagnostic blood test has been developed for amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disease that affects neurons in the brain and spinal cord. ALS leads to...
JULY 11, 2024 by Brian Burns, Massachusetts General Hospital An MRI with increased signal in the posterior part of the internal capsule which can be tracked to the motor cortex consistent with the diagnosis of ALS. Credit: Frank Gaillard/WikipediaImmune system dysregulation and elevated inflammation contribute to the development of the fatal neurodegenerative condition amyotrophic lateral...
by Umea University Credit: Pixabay/CC0 Public Domain A unique type of muscle fiber found in the extraocular muscles has been shown to be resistant against the disease amyotrophic lateral sclerosis (ALS), and has been shown to even increase in proportion to compensate when other types of muscle fibers decrease in proportion. This finding, by researchers at Umeå University...
by Cell Press Photo of iPSCs-derived Motor neurons derived from an ALS patient. Credit: Morimoto et al/Cell Stem Cell Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is a fatal motor neuron disease that causes people to gradually lose control of their muscles. There is no cure, and current treatments focus on reducing symptoms...
by Children’s Hospital Boston An MRI with increased signal in the posterior part of the internal capsule which can be tracked to the motor cortex consistent with the diagnosis of ALS. Credit: Frank Gaillard/Wikipedia While drugs are on the market to slow the progression of neurodegenerative diseases, there are still no cures. But researchers at Boston Children’s...
by Harvard John A. Paulson School of Engineering and Applied Sciences This soft robotic wearable is capable of significantly assisting upper arm and shoulder movement in people with ALS. Credit: Walsh Lab, Harvard SEAS Some 30,000 people in the U.S. are affected by amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, a neurodegenerative...
by Miguel A. Rubio, Autonomous University of Barcelona Dermis cells, control vs ELA. Credit: UAB/Hospital del Mar Researchers of the Neuroplasticity and Regeneration Group of the Universitat Autònoma de Barcelona (UAB) and of the Functional Unit for Amyotrophic Lateral Sclerosis at the Hospital del Mar have identified the presence of an ALS biomarker in the...
The largest analysis to date of genetic data in amyotrophic lateral sclerosis (ALS) – the muscle-crippling neurodegenerative disease that afflicted the late astrophysicist Stephen Hawking and cut short the career of iconic Yankee baseball slugger Lou Gehrig – has identified two previously unrecognized genetic risks that are significantly associated with the disease. In the...
A study led by Indiana University School of Medicine researchers demonstrates how electroacupuncture triggers a neurological mechanism that can help promote tissue repair and relieve injury-induced pain. Their findings, published online March 16 in the journal Stem Cells, provide the most comprehensive picture yet of how electroacupuncture stimulates the brain to facilitate the release of stem...
