by Rebecca Ferguson, University of Sheffield Results from a randomized clinical trial have shown that a potential new treatment can help control the immune response of patients with motor neuron disease (MND), which could reduce further damage in the brain and spinal cord. MND is the name for a group of diseases which affects the...
A team of researchers led by scientists at the University of Toronto (U of T) has delayed the onset of amyotrophic lateral sclerosis (ALS) in mice. They are cautiously optimistic that the result, combined with other clinical advances, points to a potential treatment for ALS in humans. Commonly known as Lou Gehrig’s disease, ALS is...
UC Riverside-led study could lead to development of small molecule drugs to treat also spinal cord injury, Alzheimer’s disease, and some cancers Amyotrophic lateral sclerosis or ALS is sometimes known as Lou Gehrig’s disease, named after the Yankees baseball player renowned for his prowess as a hitter and for his durability — a trait that...
It took eight long years of research, but now an international team led by neuroscientists at Université de Montréal has discovered a basic molecular mechanism that better helps understand how Lou Gehrig’s disease, or amyotrophic lateral sclerosis (ALS), works. And that basic science could someday lead to new therapy for the debilitating disease, which cripples...
Researchers from the University of Montréal Hospital Research Centre (CRCHUM) and the Cumming School of Medicine (CSM) at the University of Calgary have discovered a medication that could make it possible to treat individuals with amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease. An article published today in JCI Insight concludes that pimozide was found to be...
Differences in disease progression in spinal interneurons, a type of nerve cell that generally succumbs to ALS in later stages of disease. Left: Normal ALS models, showing protein aggregation (red/green) in spinal interneurons.Right Columbia scientists have discovered that one of the body’s natural defenses against amyotrophic lateral sclerosis (ALS)—a cellular ‘clean-up process’ called autophagy—suppresses...
JERSEY CITY, N.J., Aug. 8, 2017 – Mitsubishi Tanabe Pharma America, Inc., today announced RADICAVA ™ (edaravone), an intravenous therapy indicated for all adult patients diagnosed with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is now available for treatment in the United States. RADICAVA, the first FDA-approved ALS treatment option in more than 20 years,...
Neurologists have created a hands-free, thought-controlled musical instrument, which they’ve recently described in a report in Frontiers in Human Neuroscience. Researchers hope that this new instrument will help empower and rehabilitate patients with motor disabilities such as those from stroke, spinal cord injury, amputation, or amyotrophic lateral sclerosis (ALS). “The Encephalophone is a musical instrument that you control...
In fact, the research shows, death is often described as a peaceful, “unexpectedly positive” experience by those who approach it. Death is one of life’s guarantees, yet it’s something people often avoid talking about, according to study author Kurt Gray. He’s an assistant professor at the University of North Carolina at Chapel Hill. “There’s almost an...
Harvard Stem Cell Institute (HSCI) researchers have identified a compound that helps protect the cells destroyed by spinal muscular atrophy (SMA), the most frequent fatal genetic disease in children under 2 years of age. SMA is a neurodegenerative disease targeting motor neurons, the long nerve cells that relay messages from the brain to the muscles...
