Tag: <span>analgesics</span>

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Sex bias in pain research

It is increasingly clear that male and female humans and rodents process pain in different ways. And that there are important differences in the underlying mechanisms involved at genetic, molecular, cellular, and physiological levels. Despite this fact, according to a review paper from McGill University published in Nature Reviews Neuroscience, most pain research remains overwhelmingly...

Antibiotics can limit body’s ability to uptake analgesics
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Antibiotics can limit body’s ability to uptake analgesics

by Anne M Stark, Lawrence Livermore National Laboratory LLNL biologists have found manipulating the gut microbiome with antibiotics alters the uptake and effectiveness of acetaminophen. The effectiveness of drug treatments can vary widely between individuals, which can lead to decreased efficacy or increased adverse reactions. Much of the variation can be contributed to genetics, but...