by Delthia Ricks , Medical Xpress Representative IVM imaging of vaccine-activated capture of ST865 pneumococci in the liver sinusoids. Pneumococci, green; KCs, red; ECs, cyan; neutrophils, magenta. Credit: Science Translational Medicine (2023). DOI: 10.1126/scitranslmed.ade0054In findings that are nothing short of surprising, scientists have demonstrated that the liver is the site where the immune system unleashes...
Tag: <span>animal model</span>
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Not too late to repair: Gene therapy improves advanced heart failure in animal model
by Ana María Rodríguez, Baylor College of Medicine Credit: CC0 Public DomainHeart failure remains the leading cause of mortality in the U.S. During a heart attack blood stops flowing into the heart. Without oxygen, part of the heart muscle dies. The heart muscle does not regenerate; instead, it replaces dead tissue with a scar made of...
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Novel approach improves heart failure outcomes in animal model
by Ana María Rodríguez, Baylor College of Medicine Credit: Pixabay/CC0 Public DomainIn 2020, heart failure affected about 6.5 million people in the U.S. and 23 million around the world. Despite recent advances, the five-year survival rate remains approximately 50%, indicating an urgent need for a novel perspective for treating this condition. A new approach described in...
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Can drug resistant TB be reversed with a novel small molecule? Scientists turn to an animal model to find out
by Delthia Ricks, Medical Xpress Credit: Unsplash/CC0 Public Domain Tuberculosis is a major public health concern, an ancient bacterial disease that has claimed the lives of kings, presidents, poets and at least one star of Hollywood’s silver screen-era. Yet even now in the 21st century, it’s still impossible to shake the scourge. TB kills someone...
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UTSW scientists eliminate key Alzheimer’s feature in animal model
UT SOUTHWESTERN MEDICAL CENTER IMAGE: JOACHIM HERZ, M.D. CREDIT: UT SOUTHWESTERN MEDICAL CENTER A study by UT Southwestern researchers finds that changing the biochemistry of parts of brain cells abolished the formation of amyloid beta plaques in a mouse model of Alzheimer’s disease. The finding, published in eLife, might eventually lead to treatments that prevent the memory-robbing...