by Morgan Sherburne, University of Michigan In 1972, Easter Island, called Rapa Nui, famous for its moai statues, offered a new wonder: the discovery of the drugrapamycin. Over the past three decades, rapamycin, which was isolated from soil bacteria, has been applied as an immuno-suppressor in a multitude of ways, including to coat coronary stents and to reduce the...
Tag: <span>Anti-Aging</span>
The immune system’s fountain of youth
Helping the immune system clear away old cells in aging mice helped restore youthful characteristics WEIZMANN INSTITUTE OF SCIENCE If only we could keep our bodies young, healthy and energetic, even as we attain the wisdom of our years. New research at the Weizmann Institute of Science suggests this dream could be at least partly...
Anti-aging drug cocktail teases significant lifespan extension in early experiments
New research has found that a novel drug cocktail almost doubled the lifespan of a microscopic worm, the largest drug-induced lifespan extension in an animal ever reported. The study suggests that pharmacological intervention to help us live longer could be a realistic proposition. The microscopic C. elegans worms, often used in anti-aging studies, had their lifespan almost doubled after treatment with a novel triple-drug...
Molecule produced during fasting has anti-aging effect on vascular system
Diet trends like intermittent fasting and ketogenesis are proving wildly popular for their rapid weight-loss effects, but scientists are also starting to uncover how they might benefit the body in other, longer-term ways. Case in point: a molecule produced during fasting has now been found to apply the brakes to an aging of the vascular...
Disrupting genetic processes reverses aging in human cells
Research has shed new light on genetic processes that may one day lead to the development of therapies that can slow, or even reverse, how our cells age. A study led by the University of Exeter Medical School has found that certain genes and pathways that regulate splicing factors – a group of proteins in...
Mitochondrial Peptides: Their Effect on Aging
Published 07/25/18 Mitochondria have long been recognized as the metabolic powerhouse in the body, and their functionality is critical to a number of processes. Interestingly, in recent years their role in signaling is being consistently appreciated. Thus, identifying reading frames that encode peptides has been a crucial component of research. One peptide that has been a huge...
Scientists reverse aging-associated skin wrinkles and hair loss in a mouse model
A gene mutation causes wrinkled skin and hair loss; turning off that mutation restores the mouse to normal appearance UNIVERSITY OF ALABAMA AT BIRMINGHAM BIRMINGHAM, Ala. – Wrinkled skin and hair loss are hallmarks of aging. What if they could be reversed? IMAGE: THE MOUSE IN THE CENTER PHOTO SHOWS AGING-ASSOCIATED SKIN WRINKLES AND HAIR LOSS...
Protecting ribosome genes to prevent aging
AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY Aging is a process of gradual deterioration from exposure to time and the elements; this process begins with deterioration deep inside every cell. Researchers from Stanford University and the VA Palo Alto Health Care System (VAPAHCS) have identified a protein that guards cells against senescence – aging-related problems...
Marshall School of Medicine research team defines possible anti-aging intervention
MARSHALL UNIVERSITY JOAN C. EDWARDS SCHOOL OF MEDICINE HUNTINGTON, W.Va. — New research from a team at the Marshall University Joan C. Edwards School of Medicine demonstrates that the Na/K-ATPase oxidant amplification loop (NAKL) is intimately involved in the aging process and may serve as a target for anti-aging interventions. The researchers were also able to successfully demonstrate the therapeutic potential...
Key molecule of aging discovered
Every cell and every organism ages sooner or later. But why is this so? Scientists at the German Cancer Research Center in Heidelberg have now discovered for the first time a protein that represents a central switching point in the aging process. It controls the lifespan of an individual—from the fly to the human being. This opens...