by Public Library of Science One way to depict the amyloid cascade. Individual steps in the cascade may evoke distinct microglial responses. Aβ, amyloid-β; AD, Alzheimer disease; APP, amyloid precursor protein. Credit: Haass C, Selkoe D, 2022, PLOS Biology, CC-BY 4.0 (https://creativecommons.org/licenses/by/4.0/) An estimated 50 million people around the world have Alzheimer’s disease (AD), and...
