Tag: <span>Anti-angiogenic Therapy</span>

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How intestinal cancer stem cells evade anti-angiogenic therapy
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How intestinal cancer stem cells evade anti-angiogenic therapy

by Ludwig Cancer Research Credit: CC0 Public Domain A team led by Ludwig Lausanne’s Tatiana Petrova, Jeremiah Bernier-Latmani and alum Christoph Cisarovsky identified a novel mechanism by which stem cells in intestinal tumors generate new blood vessels and evade anti-angiogenic therapy. Vascular endothelial growth factor A (VEGFA) is an important supporter of both healthy and...

New bandages could help to treat diabetic and burn wounds
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New bandages could help to treat diabetic and burn wounds

by University of Sheffield New dressings that could be used to treat diabetic wounds and burns injuries more effectively have been developed by engineers from the University of Sheffield The cotton-based dressings, developed by Professor Sheila MacNeil from the University’s Department of Materials Science and Engineering, release an agent that promotes the formation of new...

New treatment extends lives of people with most common type of liver cancer
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New treatment extends lives of people with most common type of liver cancer

by University of California, Los Angeles For the first time in over a decade, scientists have identified a first-line treatment that significantly improves survival for people with hepatocellular carcinoma, the most common type of liver cancer. Researchers found that the combination of atezolizumab, an immunotherapy drug that boosts the body’s natural defenses, and bevacizumab, an...

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Marshall School of Medicine research team defines possible anti-aging intervention

MARSHALL UNIVERSITY JOAN C. EDWARDS SCHOOL OF MEDICINE  HUNTINGTON, W.Va. — New research from a team at the Marshall University Joan C. Edwards School of Medicine demonstrates that the Na/K-ATPase oxidant amplification loop (NAKL) is intimately involved in the aging process and may serve as a target for anti-aging interventions. The researchers were also able to successfully demonstrate the therapeutic potential...

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Immunosuppression Underlies Resistance to Anti-angiogenic Therapy

A Massachusetts General Hospital (MGH) research team has identified a novel mechanism behind resistance to angiogenesis inhibitors – drugs that fight cancer by suppressing the formation of new blood vessels. In their report published in the Journal of Clinical Investigation, the team based in the Edwin L. Steele Laboratories for Tumor Biology in the MGH Department of Radiation Oncology describes...