A new antibiotic uses a never-before-seen mechanism to deliver a direct hit on tough-to-treat infections while leaving beneficial microbes alone. The strategy could lead to a new class of antibiotics that attack dangerous bacteria in a powerful new way, overcoming current drug resistance while sparing the gut microbiome. “The biggest takeaway is the double-selective component,”...
Tag: <span>antibiotic</span>
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COMMON ANTIBIOTIC TIED TO HIGHER DEATH RISK IN SICKEST PATIENTS
MAY 14TH, 2024 POSTED BY U. MICHIGAN (Credit: Getty Images) Decisions about which antibiotics to give a patient when a life-threatening infection is suspected may have unintended consequences for patient outcomes, a new study reveals. Beginning in 2015, a 15-month national shortage of a commonly prescribed antibiotic, piperacillin/tazobactam, known by the brand name Zosyn, provided a unique...
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Could new antibiotic clovibactin beat superbugs? Or will it join the long list of failed drugs?
by Sacha Pidot, The Conversation Credit: Unsplash/CC0 Public Domain Imagine a world where simple infections could become life-threatening, where a small cut could spell disaster, and where doctors couldn’t treat diseases effectively anymore. This isn’t the plot of a science fiction movie—it’s a real concern. For decades, antibiotics have been used successfully to fight a wide...
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Resistant Superbugs Killed by New Antibiotic From Bacterial “Dark Matter”
Previously “unculturable” bacteria could represent a source of novel antibiotics.Published: August 22, 2023 Sarah Whelan, PhD Credit: Markus Weingarth A study has isolated a powerful new antibiotic – clovibactin – from soil bacteria previously considered “unculturable”, demonstrating that it kills bacteria in a way that is less likely to lead to antibiotic resistance. The research...
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Antibiotic shows effectiveness against deadly staph infections
by Alexis Porter, Duke University Credit: CC0 Public DomainAn antibiotic that has shown effectiveness for bacterial pneumonia also appears successful in fighting methicillin-resistant staph infections, reports a team led by Duke Health. The drug, ceftobiprole, showed similar benefit when tested against the antibiotic daptomycin to treat complicated Staphylococcus aureus bacterial infections. If approved by the...
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Researchers decode new antibiotic
UNIVERSITY OF BONN IMAGE: (FROM LEFT) ANNIKA KRÜGER, PROF. DR. TANJA SCHNEIDER, DR. STEFANIA DE BENEDETTI AND DR. FABIAN GREIN. CREDIT: PHOTO: GREGOR HÜBL/UNIVERSITY OF BONN More and more bacterial pathogens are developing resistance. There is an increasing risk that common drugs will no longer be effective against infectious diseases. That is why scientists around...
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Neglected 80-Year-Old Antibiotic Could Provide a New Way To Fight Difficult-To-Treat Infections
By PLOS JULY 10, 2023 A research team has found that Nourseothricin, an old antibiotic, could be effective against drug-resistant bacteria. Improved purification techniques have identified less toxic forms of the antibiotic, specifically Streptothricin-F, that show strong activity against Gram-negative bacteria, by binding to a bacterial ribosome subunit and inducing translation errors, offering a unique approach to...
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Doctor kills himself after taking antibiotic with ‘rare link’ to suicide
By Catherine Lough19 June 2023 • 1:01pm Robert Stevenson died around a week after he started a course of ciprofloxacin CREDIT: TEK IMAGE A retired cardiologist with no history of mental health problems took his own life one week after taking an antibiotic with a “rare” link to suicide, a coroner has found. Robert Stevenson, a...
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Investigation raises questions over lack of “substantial evidence” for FDA approved antibiotic
BMJ Drugs approved in the US require “substantial evidence” that they are effective. But an investigation by The BMJ into the recent approval of the antibiotic Recarbrio from Merck suggests that these standards are being bypassed. Peter Doshi, senior editor at The BMJ, describes how US Food and Drug Administration (FDA) scientists had serious doubts about Recarbrio...
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Artificial sweeteners found to kill off antibiotic-resistant bacteria
by Hayley Jarvis, Brunel University Credit: Brunel University Sugar substitutes found in many supermarket foods have been shown to kill off antibiotic-resistant bacteria that cause pneumonia and sepsis. Three artificial sweeteners used in products such as diet drinks, yogurts and desserts dramatically halt the growth of multidrug-resistant priority pathogens. The additives not only disable bacteria...