by American Chemical Society Credit: Pixabay/CC0 Public Domain “Back-to-school” season means buying pens and paper, figuring out the new bus route, and … earaches. Doctors typically treat these infections with antibiotics, but children don’t always complete the full course, accelerating resistance to these medications. Today, researchers report developing a single-use nanoscale system that’s unlikely to generate resistance. Using...
By IANS, TWC India Representational Image(Yogesh Kumar/BCCL Delhi) Curbing levels of harmful air pollution could help reduce antibiotic resistance, and related deaths, according to the first in-depth global analysis of the possible links between the two, published in The Lancet Planetary Health journal. The findings indicate antibiotic resistance increases with particulate matter (PM2.5) — made...
By Dr. Liji Thomas, MD Reviewed by Lily Ramsey, LLM Urinary tract infections (UTIs) are among the most common infections worldwide. Though generally minor, they can escalate to cause pyelonephritis, chronic infection, or septicemia in the elderly or high-risk population. Moreover, they may trigger the formation or growth of urinary calculi. Image Credit:Buravlevastock/Shutterstock.com The problem...
14 April 2023 By MEGAN KELLER, THE CONVERSATION Tolerant bacteria are dormant until an antibiotic threat has passed, then reemerge to conduct business as usual. (Christoph Burgstedt/Science Photo Library/Getty Images) Have you ever had a nasty infection that just won’t seem to go away? Or a runny nose that keeps coming back? You may have been...
UNIVERSITY OF WARWICK VIDEO: BACTERIA IN THE UNIVERSITY OF WARWICK STUDY. CREDIT: UNIVERSITY OF WARWICK Like the neurons firing in human brains, bacteria use electricity to communicate and respond to environmental cues. Now, researchers have discovered a way to control this electrical signalling in bacteria, to better understand resistance to antibiotics. This powerful tool will help advance...
by Hokkaido University Microtiter plates that were used in the study for the assessment of antibiotic activity. Credit: Akira Katsuyama Hokkaido University researchers have developed a novel method to design and develop peptide antibiotics in large numbers, which will prove critical to controlling antibiotic resistance. Applications of new molecules as drugs are expected to be effective in treating...
by Chalmers University of Technology The antibacterial material, with peptides bound to hydrogel particles, works even in contact with body fluids such as blood. It can be sprayed directly into wounds without impairing healing or applied as a coating to catheters and implants to prevent infection, and to fight even multi-resistant bacteria. Credit: Chalmers University...
NARA INSTITUTE OF SCIENCE AND TECHNOLOGY IMAGE: SCHEMATIC OF THE INTELLIGENT IMPEDANCE SYSTEM, CONSISTING OF A PARALLEL IMPEDANCE CYTOMETRY AND A MACHINE LEARNING-BASED DETECTION SYSTEM. IN THE CASE OF SINGLE BACTERIA DETECTION, UNTREATED BACTERIA CELLS WERE MEASURED IN ONE CHANNEL AS THE REFERENCE, AND ANTIBIOTIC-TREATED CELLS WERE MEASURED IN ANOTHER CHANNEL AS THE TARGET PARTICLES....
A new class of motorized molecules that kill specific bacteria shows promise to curb the threat of antibiotic resistance to human health. Rice University scientists led a team developing light-activated hemithioindigo (HTI) molecules that destroy Gram-positive bacteria and the biofilms they form. The molecules enhance the local generation of reactive oxygen species (ROS) that chemically attack and destroy drug-resistant cells. The new molecules...
by Harry Perkins Institute of Medical Research Susceptibility-associated signatures are associated with antimicrobial effect. When assayed using our FAST protocol, population-level changes in multiparametric distribution can be observed as reproducible patterns of deviation from the antimicrobial unexposed population (bounded in purple). Absence of these patterns can be used to determine a lack of susceptibility (i.e., resistance)...
