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Test determines antibiotic resistance in less than 90 minutes
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Test determines antibiotic resistance in less than 90 minutes

by Washington State University Postdoctoral researcher Abdelrhman Mohamed and graduate student Gretchen Tibbitts used an electric probe to measure bacterial electrochemical signals and to identify antibiotic resistance in less than 90 minutes. Credit: WSU A technique that measures the metabolic activity of bacteria with an electric probe can identify antibiotic resistance in less than 90...

Lower antibiotic resistance in intestinal bacteria with forgotten antibiotic
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Lower antibiotic resistance in intestinal bacteria with forgotten antibiotic

by Linköping University Escherichia coli. Credit: Rocky Mountain Laboratories, NIAID, NIH A forgotten antibiotic, temocillin, led to lower selection of resistant bacteria than the standard treatment for febrile urinary tract infection, in a study published in The Lancet Infectious Diseases. Thus, temocillin may be useful in treating severe urinary tract infections that give rise to fever,...

Biochemists detail protein vital to tuberculosis, antibiotic resistance
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Biochemists detail protein vital to tuberculosis, antibiotic resistance

It’s as true in the realm of infectious disease as combat. And the University of Nebraska–Lincoln’s Limei Zhang subscribes to the maxim that best encapsulates it. “In order to fight your enemies, you have to know how your enemies survive and attack you,” said Zhang, associate professor of biochemistry. “That’s the fundamental question we are looking at.”...

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DRUG COMBOS THAT SPARK ANTIBIOTIC RESISTANCE

The research could help doctors optimize the choice, timing, dose, and sequence of antibiotics used to treat common infections in order to help halt the growing threat of antibiotic resistance to modern medicine. “Drug combinations are a particularly promising approach for slowing resistance, but the evolutionary impacts of combination therapy remain difficult to predict, especially...

Where antibiotic resistance comes from
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Where antibiotic resistance comes from

UNIVERSITY OF GOTHENBURG IMAGE: PROF. JOAKIM LARSSON, SAHLGRENSKA ACADEMY, UNIVERSITY OF GOTHENBURG. CREDIT: PHOTO BY JOHAN WINGBORG By comparing thousands of bacterial genomes, scientists in Gothenburg, Sweden have traced back the evolutionary history of antibiotic resistance genes. In almost all cases where an origin could be determined, the gene started to spread from bacteria that,...

Alzheimer’s disease drug may help fight against antibiotic resistance
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Alzheimer’s disease drug may help fight against antibiotic resistance

by  University of Queensland UQ’s Dr David De Oliveira in the lab, testing the efficacy of PBT2 in disrupting and killing antibiotic-resistant Gram-negative bacteria. An experimental Alzheimer’s disease treatment is proving effective at treating some of the most persistent, life-threatening antibiotic-resistant bacteria. Researchers from The University of Queensland, The University of Melbourne and Griffith University have discovered...

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Next frontier in bacterial engineering

PRINT E-MAIL From bacteria-made insulin that obviates the use of animal pancreases to a better understanding of infectious diseases and improved treatments, genetic engineering of bacteria has redefined modern medicine. Yet, serious limitations remain that hamper| progress in numerous other areas. A decades-old bacterial engineering technique called recombineering (recombination-mediated genetic engineering) allows scientists to scarlessly...

Metals could replace conventional antibiotics if antibiotic resistance continues to increase
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Metals could replace conventional antibiotics if antibiotic resistance continues to increase

The world is facing a huge problem of antibiotic resistant bacteria. Once our medicine stops working against bacterial infections, we are going to be in huge trouble. But scientists are already looking for alternative approaches. One of them could be metals, as indicated by this new study from the University of Queensland. Various bacteria are...

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Closest Look Yet at Killer T-cell Activity Could Yield New Approach to Tackling Antibiotic Resistance

ANN ARBOR — In a study that could provide a roadmap for combatting the rising threat of drug-resistant pathogens, researchers have discovered the specific mechanism the body’s T cells use to kill bacteria. University of Michigan researchers, in collaboration with colleagues at Harvard University, have discovered a key difference between the way immune cells attack...