JUNE 28, 2024 by University of Copenhagen Credit: Unsplash/CC0 Public DomainOlder GPs are more likely to prescribe antibiotics than their younger colleagues. A more cautious approach will not degrade treatment—and it can help fight antibiotic resistance that could soon kill millions of people annually. The discovery was made in a new study from the Department...
A new antibiotic uses a never-before-seen mechanism to deliver a direct hit on tough-to-treat infections while leaving beneficial microbes alone. The strategy could lead to a new class of antibiotics that attack dangerous bacteria in a powerful new way, overcoming current drug resistance while sparing the gut microbiome. “The biggest takeaway is the double-selective component,”...
MAY 14TH, 2024 POSTED BY U. MICHIGAN (Credit: Getty Images) Decisions about which antibiotics to give a patient when a life-threatening infection is suspected may have unintended consequences for patient outcomes, a new study reveals. Beginning in 2015, a 15-month national shortage of a commonly prescribed antibiotic, piperacillin/tazobactam, known by the brand name Zosyn, provided a unique...
by Sacha Pidot, The Conversation Credit: Unsplash/CC0 Public Domain Imagine a world where simple infections could become life-threatening, where a small cut could spell disaster, and where doctors couldn’t treat diseases effectively anymore. This isn’t the plot of a science fiction movie—it’s a real concern. For decades, antibiotics have been used successfully to fight a wide...
Previously “unculturable” bacteria could represent a source of novel antibiotics.Published: August 22, 2023 Sarah Whelan, PhD Credit: Markus Weingarth A study has isolated a powerful new antibiotic – clovibactin – from soil bacteria previously considered “unculturable”, demonstrating that it kills bacteria in a way that is less likely to lead to antibiotic resistance. The research...
by Alexis Porter, Duke University Credit: CC0 Public DomainAn antibiotic that has shown effectiveness for bacterial pneumonia also appears successful in fighting methicillin-resistant staph infections, reports a team led by Duke Health. The drug, ceftobiprole, showed similar benefit when tested against the antibiotic daptomycin to treat complicated Staphylococcus aureus bacterial infections. If approved by the...
UNIVERSITY OF BONN IMAGE: (FROM LEFT) ANNIKA KRÜGER, PROF. DR. TANJA SCHNEIDER, DR. STEFANIA DE BENEDETTI AND DR. FABIAN GREIN. CREDIT: PHOTO: GREGOR HÜBL/UNIVERSITY OF BONN More and more bacterial pathogens are developing resistance. There is an increasing risk that common drugs will no longer be effective against infectious diseases. That is why scientists around...
By PLOS JULY 10, 2023 A research team has found that Nourseothricin, an old antibiotic, could be effective against drug-resistant bacteria. Improved purification techniques have identified less toxic forms of the antibiotic, specifically Streptothricin-F, that show strong activity against Gram-negative bacteria, by binding to a bacterial ribosome subunit and inducing translation errors, offering a unique approach to...
By Catherine Lough19 June 2023 • 1:01pm Robert Stevenson died around a week after he started a course of ciprofloxacin CREDIT: TEK IMAGE A retired cardiologist with no history of mental health problems took his own life one week after taking an antibiotic with a “rare” link to suicide, a coroner has found. Robert Stevenson, a...
BMJ Drugs approved in the US require “substantial evidence” that they are effective. But an investigation by The BMJ into the recent approval of the antibiotic Recarbrio from Merck suggests that these standards are being bypassed. Peter Doshi, senior editor at The BMJ, describes how US Food and Drug Administration (FDA) scientists had serious doubts about Recarbrio...
