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Research reveals human immune system reduces potency of antibiotics

UNIVERSITY OF KENT Research from the University of Kent’s School of Biosciences has revealed that a molecule produced by the human immune system can severely diminish the potency of certain antibiotics.  This may explain why antibiotics effective in laboratory settings can be less effective at clearing infections in humans.  The research findings, which have been...

Five days of antibiotics fine for children with pneumonia
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Five days of antibiotics fine for children with pneumonia

by  McMaster University Associate professor of pediatrics of McMaster’s Michael G. DeGroote School of Medicine and an infectious disease pediatrician for Hamilton Health Sciences. Credit: McMaster University Many parents know the struggle of having to make children with pneumonia finish the usual 10-day course in antibiotics despite the child feeling better after a few days of...

X-factor to help antibiotics regain their spark
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X-factor to help antibiotics regain their spark

Holding off the rise of superbugs could be achieved by ‘resuscitating’ old antibiotics, with The University of Queensland researchers leading an international project to help combat the growing threat. CARB-X, a global non-profit partnership funding the world’s largest antibacterial development pipeline, has funded the $AU2.9m project at UQ’s Institute for Molecular Bioscience (IMB). Drs Mark Blaskovich, Alysha Elliott and Johanne...

Exposure to superbacteria among visitors to the tropics more extensive than previously thought
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Exposure to superbacteria among visitors to the tropics more extensive than previously thought

by  University of Helsinki Credit: Unsplash/CC0 Public Domain Exploring exposure to superbacteria, researchers at the University of Helsinki and Helsinki University Hospital got unexpected results from an international collaborative study conducted in real time among 20 travelers to Southeast Asia. All the participants were found to contract superbacteria within a week after arriving in the destination. A detailed...

Three longtime antibiotics could offer alternative to addictive opioid pain relievers
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Three longtime antibiotics could offer alternative to addictive opioid pain relievers

by  UT Southwestern Medical Center This illustration shows the atomic level resolution of the tetracycline antibiotic bound to the EphB1 receptor. Credit: UT Southwestern Medical Center Three decades-old antibiotics administered together can block a type of pain triggered by nerve damage in an animal model, UT Southwestern researchers report. The finding, published online today in PNAS, could offer an...

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Why people overuse antibiotics

RUTGERS UNIVERSITY The overuse of antibiotics occurs due to the mistaken widespread belief that they are beneficial for a broad array of conditions and because many physicians are willing to prescribe antibiotics if patients ask for the medication, according to a Rutgers study.  The study, published in the journal BioEssays, reviewed more than 200 peer-reviewed...

Treatment success seen with antibiotics for uncomplicated appendicitis
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Treatment success seen with antibiotics for uncomplicated appendicitis

JANUARY 12, 2021 (HealthDay)—For adults with uncomplicated acute appendicitis, treatment success rates ≥65 percent are seen with both oral antibiotics and combined intravenous and oral antibiotics, according to a study published online Jan. 11 in the Journal of the American Medical Association. Suvi Sippola, M.D., from Turku University Hospital in Finland, and colleagues compared oral antibiotics...

Phage viruses can make superbugs susceptible to antibiotics again
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Phage viruses can make superbugs susceptible to antibiotics again

By Michael Irving January 12, 2021 Researchers have found that bacteria-killing viruses could help make superbugs susceptible to antibiotics once again iLexx/Deposit photos VIEW 1 IMAGES Viruses firmly hold the world’s attention at the moment, but we shouldn’t ignore the rising health threat that bacteria pose, too. The crafty critters are fast evolving resistance to...

Fluoride to the Rescue?
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Fluoride to the Rescue?

Scientists have long been aware of the dangerous overuse of antibiotics and the increasing number of antibiotic-resistant microbes that have resulted. While over-prescription of antibiotics for medicinal use has unsettling implications for human health, so too does the increasing presence of antibiotics in the natural environment. The latter may stem from the improper disposal of...

Research team reports new class of antibiotics active against a wide range of bacteria
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Research team reports new class of antibiotics active against a wide range of bacteria

by  The Wistar Institute Bacteria image. Credit: The Wistar Institute Wistar Institute scientists have discovered a new class of compounds that uniquely combine direct antibiotic killing of pan drug-resistant bacterial pathogens with a simultaneous rapid immune response for combatting antimicrobial resistance (AMR). These finding were published today in Nature. The World Health Organization (WHO) has declared AMR...