Sponsored Content by St John’s Laboratory Enzyme Linked Immunosorbent Assay (ELISA) is a basic, sensitive, reliable, and efficient analytical method employed for the quantification and detection of protein biomarkers in immunoassays.1 How Does an ELISA Work? The ELISA method is established on the strength of the interaction between an antigen and an antibody, frequently called the binding specificity and...
Tag: <span>antibodies</span>
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Virus characteristics predict HIV treatment efficacy with antibody treatment
BOSTON MEDICAL CENTER BOSTON – Current HIV-1 therapies have been proven to be highly effective in slowing the progression of the virus in the body with only minimal side effects. The daily antiretroviral therapy (ART) uses a combination of HIV-1 medicines. A proportion of patients diagnosed with HIV-1, however, cannot take the ART for many...
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Easier Way of Sneaking Antibodies into Cells
For almost any conceivable protein, corresponding antibodies can be developed to block it from binding or changing shape, which ultimately prevents it from carrying out its normal function. As such, scientists have looked to antibodies as a way of shutting down proteins inside cells for decades, but there is still no consistent way to get...
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Novel antibodies could provide a universal flu vaccine
Currently available flu vaccines are based on the rapidly changing viral hemagglutinin (HA) antigen, and are therefore quickly outdated. Thus new vaccines need to be developed each year. Now, a new study published in the journal Science on October 25, 2019, reports on a set of three novel antibodies that bind to another type of...
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Study reveals more about how immune cells create new types of antibodies
by Bob Yirka , Medical Xpress A team of researchers at Boston Children’s Hospital has learned more about the process of V(D)J recombination and how it makes use of chromatin looping to collect segments that are to be spliced. In their paper published in the journal Nature, the researchers outline their research and what they...
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By targeting flu-enabling protein, antibody may protect against wide-ranging strains
The findings could lead to a universal flu vaccine and more effective emergency treatments SCRIPPS RESEARCH INSTITUTE LA JOLLA, CA – A nationwide team of researchers has found an antibody that protects mice against a wide range of potentially lethal influenza viruses, advancing efforts to design of a universal vaccine that could either treat or...
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Antibiotics found in some of the world’s rivers exceed ‘safe’ levels, global study finds
UNIVERSITY OF YORK Concentrations of antibiotics found in some of the world’s rivers exceed ‘safe’ levels by up to 300 times, the first ever global study has discovered. Researchers looked for 14 commonly used antibiotics in rivers in 72 countries across six continents and found antibiotics at 65% of the sites monitored. Metronidazole, which is used to treat bacterial infections including skin...
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Using Antibodies to Detect the Expression of Neural Stem Cell Markers
by Atlas Antibodies Neural Stem Cells Collectively, markers against neural stem cells (NSCs) represent a robust tool in basic research and advanced regenerative medicine. Studies focused on differentiation toward specific neural lineages are supported by changes in the expression levels of specific markers, which can help to identify the presence of neural stem cells. Nestin and SOX2 are two commonly utilized markers for NSCs. Other markers expressed at the cellsurface are ABCG2, FGFR1 and Frizzled-9. NSCs differentiate into...
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Directed evolution gets bacteria designing new antibiotics for us
Evolution is an incredible process, allowing life to adapt to changes in its environment. In the 1990s, the lab of Frances Arnold showed how we can turn this process to our advantage by manipulating microbes into evolving in a certain way, which could lead to new drugs and other breakthroughs. The discovery earned Arnold the 2018 Nobel Prize in...
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Scientists delineate pathway that helps us make antibodies
MEDICAL COLLEGE OF GEORGIA AT AUGUSTA UNIVERSITY AUGUSTA, Ga. (March 13, 2019) – Our bodies are continuously concocting specific antibodies to thwart invaders like a virus or even pollen, and scientists have new information about how the essential production gets fired up and keeps up. It’s a key protective mechanism that the scientists want to...