The virus today is not the same as the one that first sickened people back in December 2019. Many of the variants circulating now are partially resistant to some of the antibody-based therapeutics that were developed based on the original virus. As the pandemic continues, more variants inevitably will arise, and the problem of resistance...
Tag: <span>Antibody</span>
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COVID-19 antibody study shows downside of not receiving second shot
by Northwestern University Thomas McDade in his Northwestern University lab testing for SARS-CoV-2 (the virus that causes COVID-19) antibodies. Credit: Northwestern University A new study shows that two months after the second Pfizer/Moderna vaccination, antibody response decreases 20% in adults with prior cases of COVID-19. The study also tests how well current vaccines resist emerging variants....
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Antibody highs and lows in survivors of Ebola
by University of Liverpool Convalescent plasma donation at the blood bank Connaught Hospital, Freetown, Sierra Leone. Credit: Professor Calum Semple A high proportion of survivors of Ebola experienced a resurgence in antibody levels nearly a year after recovery, a new University of Liverpool study has found. Published today in Nature, the finding hints that hidden reservoirs of...
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Seasonal flu vaccinations don’t ‘stick’ long-term in bone marrow
A study from Emory Vaccine Center provides insights into why the boost in immunity from seasonal flu vaccination lasts for months but not years, unlike some childhood vaccinations. The home base for immune cells that produce antibodies is the bone marrow. Seasonal flu vaccination does increase the number of antibody-producing cells specific for flu in...
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Patients taking long-term opioids produce antibodies against the drugs
by Eric Hamilton, University of Wisconsin-Madison University of Wisconsin-Madison scientists have discovered that a majority of back-pain patients they tested who were taking opioid painkillers produced anti-opioid antibodies. These antibodies may contribute to some of the negative side effects of long-term opioid use. Existing antibodies may also limit the benefit a patient receives from an...
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Study shows frequently used serology test may not detect antibodies that could confirm protection against reinfection of COVID-19
SARS-CoV-2 antibody serology assays developed by MD Anderson researchers accurately detect neutralizing antibodies UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER RAGHU KALLURI, M.D., PH.D. view more CREDIT: THE UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER HOUSTON — Two different types of detectable antibody responses in SARS-CoV-2 (COVID-19) tell very different stories and may indicate...
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How COVID-19 might increase risk of memory loss and cognitive decline
by Natalie C. Tronson, The Conversation Of all frightening ways that the SARS-COV-2 virus affects the body, one of the more insidious is the effect of COVID-19 on the brain. It is now clear that many patients suffering from COVID-19 exhibit neurological symptoms, from loss of smell, to delirium, to an increased risk of stroke....
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Cutting edge synthetic peptides block SARS-CoV-2 (COVID-19)
By Sally Robertson, B.Sc. Researchers at Ligandal Inc., the University of California San Francisco and Toyota Technological Institute at Chicago, have designed novel synthetic peptides that potently inhibit the ability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to infect host cells. The team’s SARS-BLOCK™ peptides competitively inhibit the receptor-binding domain (RBD) on the SARS-CoV-2...
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Immunotherapy-resistant cancers eliminated in mouse study
Antibody that blocks TREM2 protein frees immune cells to reject cancer WASHINGTON UNIVERSITY SCHOOL OF MEDICINE IMMUNE CELLS INFILTRATE A HUMAN TUMOR IN THE FOUR COLORIZED IMAGES ABOVE. IN A MOUSE STUDY, RESEARCHERS AT WASHINGTON UNIVERSITY SCHOOL OF MEDICINE IN ST. LOUIS HAVE FOUND THAT AN… view more CREDIT: WILLIAM VERMI/MARTINA MOLGORA Immunotherapy has revolutionized...
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Gut microbes shape our antibodies before we are infected by pathogens
PROF. DR. RER. NAT. STEPHANIE GANAL-VONARBURG DEPARTMENT FOR BIOMEDICAL RESEARCH (DBMR), UNIVERSITY OF BERN, AND UNIVERSITY CLINIC OF VISCERAL SURGERY AND MEDICINE OF THE INSELSPITAL, UNIVERSITY HOSPITAL BERN view more CREDIT: COURTESY OF STEPHANIE GANAL-VONARBURG B cells are white blood cells that develop to produce antibodies. These antibodies, or immunoglobulins, can bind to harmful foreign...