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Antidepressants DON’T make people any happier, major study claims
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Antidepressants DON’T make people any happier, major study claims

By JOE DAVIES HEALTH REPORTER FOR MAILONLINE PUBLISHED: 13:00 EDT, 20 April 2022 | UPDATED: 17:42 EDT, 20 April 2022 Antidepressants are no better at making people feel happier than taking no medication at all, a study claimed today.  Patients on the drugs did not have a significantly better quality of life compared to depressed people who were not on...

Prescribe fewer antidepressants, and for shorter periods, doctors advised
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Prescribe fewer antidepressants, and for shorter periods, doctors advised

by  British Medical Journal Credit: Unsplash/CC0 Public Domain Doctors should prescribe fewer antidepressants and for shorter periods of time, because of the ongoing uncertainties about their effectiveness and the potential severity and durability of the withdrawal symptoms associated with them, suggests a review of the evidence on antidepressant use, published online in the Drug and Therapeutics Bulletin....

Antidepressants plus common painkillers may raise bleeding risk
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Antidepressants plus common painkillers may raise bleeding risk

by Steven Reinberg  (HealthDay)—Antidepressants called selective serotonin reuptake inhibitors (SSRIs) are a mainstay of depression treatment, but a new study warns that taking common painkillers alongside SSRIs may raise the chances for intestinal bleeding. In a review of 10 published studies involving 6,000 patients, researchers found that those taking SSRIs (such as Celexa, Paxil, Prozac...

Antidepressants inhibit cancer growth in mice
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Antidepressants inhibit cancer growth in mice

by  University of Zurich Fig. S1. Syngeneic murine tumor cell growth & efficacy of serotonin depletion and reconstitution therapies in Wt and Tph1-/- mice. (A and B) Tumor weight at the end of the experiment after s.c. injection of syngeneic murine 5*105 MC38 (day 28) and 1*106 Panc02 cell lines (day 35) in Wt and Tph1-/-...

Best evidence suggests antidepressants aren’t very effective in kids and teens. What can be done instead?
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Best evidence suggests antidepressants aren’t very effective in kids and teens. What can be done instead?

by Sarah Hetrick, Joanne McKenzie, Nick Meader and Sally Merry,  The Conversation Credit: Shutterstock Even before COVID-19 lockdowns, school closures and strict social distancing, depression was on the rise in children and teenagers around the globe. By the age of 19, around 25% of adolescents are estimated to have experienced a depressive episode. By the age of 30, this figure grows...

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Why is it so hard to withdraw from some antidepressants?

UNIVERSITY OF ILLINOIS AT CHICAGO Researchers at the University of Illinois Chicago are a step closer to discovering why it is so difficult for people to withdraw from some antidepressant medications.  The paper “Antidepressants produce persistent Gαs associated signaling changes in lipid rafts following drug withdrawal,” published in the journal Molecular Pharmacology, addresses the molecular and cellular...

Discontinuing antidepressants requires careful planning
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Discontinuing antidepressants requires careful planning

by Riitta Partanen,  University of Queensland Credit: Unsplash/CC0 Public Domain The decision to stop prescribing long-term anti-depressants should be made only after careful preparation by GPs and their patients, University of Queensland research has found. The qualitative study was based on interviews with 22 GPs working in urban and regional areas, who said there was no standardized approach....

Nasal spray approved for treating suicidal people
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Nasal spray approved for treating suicidal people

by Cynthia Koons Johnson & Johnson’s Spravato has been approved as the first antidepressant for actively suicidal people, as doctors are becoming increasingly concerned about COVID-19’s effect on the mental health of Americans. The Food and Drug Administration approval means the quick-acting nasal spray will be available to people with suicidal thoughts and a plan...

Study among first to explore link between antidepressants during pregnancy and child development in kindergarten
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Study among first to explore link between antidepressants during pregnancy and child development in kindergarten

by University of Manitoba Children whose mothers had depression and took serotonergic antidepressants during pregnancy have an increased risk of deficits in language and cognition, compared to children of mothers who had depression during pregnancy and did not take antidepressants, according to findings in a new University of Manitoba study published today in Pediatrics, the...