MASSACHUSETTS GENERAL HOSPITAL BOSTON – The antiepileptic drug ezogabine reduced pathologic excitability of cortical and spinal motor neuron cells that are early signs of clinical dysfunction in people with amyotrophic lateral sclerosis (ALS), according to a study conducted by the Neurological Clinical Research Institute of Massachusetts General Hospital (MGH). In addition to providing a clearer understanding of...
Tag: <span>Antiepileptic drug</span>
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Antiepileptic drug exposure in pregnancy and neurodevelopmental disorder risk
by Nature Publishing Group Children born to mothers who took the antiepileptic drug sodium valproate during pregnancy may have a four to five-fold increased risk of developing neurodevelopmental disorders in early childhood, according to a study in Scientific Reports. Fifty of the 991 French children (5%) who were exposed to sodium valproate were diagnosed with neurodevelopmental disorders...