News Release 16-Sep-2024 Peer-Reviewed PublicationUniversity of Cambridge Monoclonal antibodies – treatments developed by cloning a cell that makes an antibody – could help provide an answer to the growing problem of antimicrobial resistance, say scientists. A team lead by researchers at the University of Cambridge has developed a monoclonal antibody drug, using a technique involving...
Tag: <span>antimicrobial resistance</span>
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Metagenomic sequencing outperforms conventional tests to identify antimicrobial resistance in bloodstream infections
by European Society of Clinical Microbiology and Infectious Diseases Credit: CC0 Public Domain Metagenomic sequencing can provide rapid and actionable antimicrobial resistance predictions to treat bloodstream infections much faster than conventional laboratory tests, and has the potential to save lives and better manage the use of antibiotics, according to new research being presented at this year’s European...
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Human body is a breeding ground for antimicrobial resistance genes, shows new study
by Earlham Institute Two distinct clusters apparent in the global landscape of adult gut resistome profiles. a NMDS projection of Bray–Curtis dissimilarities among the log-transformed ARG family profiles (cpg) in adult gut metagenomes (contours estimate sample densities). Samples were colored by cluster assignment (PAM, Bray-Curtis clustering, k=2). b Average silhouette width of PAM Bray-Curtis clusters as...
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Study finds antimicrobial resistance is making UTIs more deadly
by CSIRO Extended-spectrum ß-lactamase-producing (ESBLs) Enterobacteriaceae bacteria: Escherichia coli. Credit: CSIRO Antimicrobial resistance (AMR) occurs when bacteria and other microbes become resistant to the drugs designed to kill them, generally through misuse or overuse of the drugs. There are two ways resistant bacteria can be passed between humans: hospital transmission and community transmission. Hospital acquired...
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Global microbiome study discovers thousands of new species, maps urban antimicrobial resistance and reveals new drug candidates
WEILL CORNELL MEDICINE NEW YORK (May 26, 2021) — About 12,000 bacteria and viruses collected in a sampling from public transit systems and hospitals around the world from 2015 to 2017 had never before been identified, according to a study by the International MetaSUB Consortium, a global effort at tracking microbes that is led by...
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Diphtheria risks becoming major global threat again as it evolves antimicrobial resistance
by University of Cambridge This photomicrograph depicted a number of Gram-positive Corynebacterium diphtheriae bacteria, which had been stained using the methylene blue technique. Credit: CDC/ Public Domain Diphtheria—a relatively easily-preventable infection—is evolving to become resistant to a number of classes of antibiotics and in future could lead to vaccine escape, warn an international team of researchers...