August 13, 2024 by Valerie Goodwin, University of Michigan Metabolic parameters in neutrophils from people in the control group, patients with APS, patients with aPL-only, and patients with Thromb (aPL–). Credit: Journal of Clinical Investigation (2024). DOI: 10.1172/JCI169893Neutrophils are an important type of white blood cell that help your immune system fight infections. One of...
by Valerie Goodwin, University of Michigan Associations between patient-reported outcomes for physical function, cognitive function, and pain intensity (n = 130 for A and C; n = 139 for B). Pearson r and associated P values are indicated. aPL, antiphospholipid antibodies; APS, antiphospholipid syndrome. Credit: ACR Open Rheumatology (2022). DOI: 10.1002/acr2.11512 Antiphospholipid syndrome is an autoimmune disease that preferentially affects women. Patients with APS are...
by Bob Yirka , Medical Xpress The recognition of EPCR-LBPA by aPLs promotes autoimmunity. Credit: Science (2021). DOI: 10.1126/science.abc0956 A team of researchers affiliated with multiple institutions in Germany and the U.S. have found a cell-surface target for autoantibodies targeting phospholipids (aPL) that contribute to antiphospholipid syndrome (APS). In their paper published in the journal Science, the group describes how...
