Tag: <span>antisense oligonucleotide</span>

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Antisense oligonucleotide treatment shows promise in treating Parkinson’s disease progression
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Antisense oligonucleotide treatment shows promise in treating Parkinson’s disease progression

NEWS RELEASE 25-JUL-2024 Peer-Reviewed PublicationTOKYO MEDICAL AND DENTAL UNIVERSITY IMAGE: RESEARCHERS FROM JAPAN INVESTIGATED HOW ASOS ADMINISTERED LOCALLY INTO THE BRAINS OF MICE MODELS FOR PARKINSON’S DISEASE CAN HELP PREVENT THE FORMATION AND SPREAD OF HARMFUL ASYN AGGREGATES THROUGH DIFFERENT REGIONS. THEIR FINDINGS SHOW ASOS COULD BE A PROMOTING THERAPEUTIC STRATEGY TO BOTH PREVENT AND...

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UMass Chan clinical trial shows antisense oligonucleotide safely suppresses mutant ALS gene in pilot human study

UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL WORCESTER, Mass. – Using a short, synthetic chain of chemically modified nucleotides engineered in the RNA Therapeutics Institute at UMass Chan Medical School, Robert H. Brown Jr., DPhil, MD, Jonathan Watts, Ph.D., and colleagues have shown the ability to suppress mutant forms of an ALS gene known as C9ORF72 in...