by Melissa Rohman, Northwestern University Representative composite image of a breast cancer specimen stained by multi-color IHC comprising CD8, Ki67, GCLC, GPX4, 923 A2AR, PanCK and DAPI. Representative CD8+GPX4+ (blue arrow), CD8+GCLC+ (blue arrowhead), CD8+GPX4+GCLC+ 924 (red arrow), and CD8+Ki67+ GPX4+GCLC+ (red arrowhead) cells. Credit: Bin Zhang, PhDA recent Northwestern Medicine study has discovered a...
Synthetic DNA nanovaccines enhance killer T cell immunity resulting in tumor control in preclinical studies THE WISTAR INSTITUTE IMAGE: L-R: WISTAR SCIENTISTS DRS. DAVID WEINER & DAN KULP CREDIT: THE WISTAR INSTITUTE Researchers designed DLnano-vaccines displaying 60 copies of protein parts derived from the melanoma-specific antigens Trp2 and Gp100 and tested these in mouse models of melanoma,...
Tweaking the adenovirus spike protein induces a more robust immune reaction for a cancer vaccine against gastric, pancreatic, esophageal and colon malignancies in animal models. THOMAS JEFFERSON UNIVERSITY PHILADELPHIA – Jefferson researchers developing a cancer vaccine to prevent recurrences of gastric, pancreatic, esophageal and colon cancers have added a component that would make the vaccine...
This news or article is intended for readers with certain scientific or professional knowledge in the field. NK cells mean Natural Killer cells. They are part of the innate immune system. They are known primarily for their ability to recognize and kill tumor cells, cells infected by viruses and bacteria, or dying by apoptosis. Although...
Scientists of the Pacific Institute of Bioorganic Chemistry (PIBOC) of the Far Eastern Branch of the Russian Academy of Sciences (FEB RAS) and the Far Eastern Federal University (FEFU) found out marine invertebrates living in Troitsa Bay, the Sea of Japan, contain biologically active compounds with strong antitumor and antimicrobial properties, and also capable of...
