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Understanding sex-specific differences in aortic aneurysms
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Understanding sex-specific differences in aortic aneurysms

September 23, 2024 by University of Kentucky Graphical abstract. Credit: Journal of Clinical Investigation (2024). DOI: 10.1172/JCI169085A group of researchers at the University of Kentucky have found a mechanism that would explain why men develop more aortic aneurysms than women. The study titled “Androgen aggravates aortic aneurysms via suppression of PD-1 in mice,” accompanied by...

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Study in mice finds erectile dysfunction medication worsened abdominal aortic aneurysms

by American Heart Association Credit: Unsplash/CC0 Public Domain In a laboratory study in mice, sildenafil, a commonly used erectile dysfunction medication, was found to worsen abdominal aortic aneurysms, indicating additional research may be needed to determine if the medication may have the same effect on people, according to new research published today in the Journal of...

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Attacking aortic aneurysms before they grow

MICHIGAN MEDICINE – UNIVERSITY OF MICHIGAN A new study investigates a genetic culprit behind abdominal aortic aneurysm, a serious condition that puts people at risk of their aorta rupturing – a potentially deadly event. Finding a viable genetic target for AAA could change the game, says senior author Katherine Gallagher, M.D., a vascular surgeon and...