by Tulane University Principal component analysis (PCA) indicates plaque rupture is associated with alterations in the transcriptome. (A) PCA plot of the top 1750 most variable transcripts in asymptomatic and recently ruptured plaques. (B) Gene ontology of the transcripts associated with recently ruptured plaques. (C) Gene ontology of the transcripts associated with asymptomatic plaques. Scientific Reports (2022). DOI:...