Osteoarthritis, which causes stiff and painful joints, affects the knees most often.Credit: Dr. P. Marazzi/Science Photo Library A blockbuster weight-loss drug sharply reduces pain from obesity-related knee arthritis and improves a person’s ability to engage in activities such as walking. That’s according to a clinical trial conducted in 11 countries — the first of its kind to...
Tag: <span>arthiritis</span>
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New type of stem cell contains potential for knee cartilage regeneration in arthritic mice
by International Society for Stem Cell Research A potentially alternative treatment for OA, a debilitating joint disease that affects more than 500 million people worldwide, is the regeneration of cartilage from stem cells. Learn more in Stem Cell Reports about the new work from Zhonghan Li and colleagues that focused on so-called limb bud progenitor...
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Low-dose oral prednisolone substantially improves pain and function in hand OA
by American College of Rheumatology Research presented at the 2019 ACR/ARP Annual Meeting found that a six-week treatment with low-dose oral prednisolone substantially improves pain and decreases signs of inflammation in patients with painful hand osteoarthritis (Abstract #1760). Osteoarthritis (also known as OA) is a common joint disease that most often affects middle-age to elderly...
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ADA2 is a specific biomarker for MAS in systemic JIA
by American College of Rheumatology According to new research findings presented at the 2019 ACR/ARP Annual Meeting, adenosine deaminase 2 (ADA2) in the peripheral blood is a sensitive, specific biomarker for macrophage activation syndrome, a potentially life-threatening complication of systemic juvenile idiopathic arthritis (systemic JIA) (Abstract #920). About one child in every 1,000 develops some...
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WSU study identifies potential new target for treatment of gout
Research team discovers alternate pathway by which MSU crystals trigger inflammation WASHINGTON STATE UNIVERSITY SPOKANE, Wash. – Researchers at Washington State University Health Sciences Spokane and elsewhere have identified a new therapeutic target for the treatment of gout, a common type of arthritis that causes episodes of painful and stiff joints. Published in the journal...
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Anti-arthritis drug also stops tuberculosis bacillus from multiplying in blood stem cells
KU LEUVEN Immunologist Johan Van Weyenbergh (KU Leuven) and his Belgian-Brazilian colleagues have shown that a drug used to fight arthritis also stops the process that allows the tuberculosis bacillus to infect and hijack blood stem cells. Tuberculosis (TB) may affect any part of the body, but the spread of the disease might start in the bone marrow. Immunologists from KU Leuven and Brazil have shown that the...
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New pain-blocking brain mechanism may relieve arthritis
Researchers have found that an experimental compound works in the amygdala to quell the pain of arthritis in rats. Experiments in rodents suggest that pain relief in arthritis originates in the brain. Pain is an alert that something is wrong — unfortunately, the pain does not go away while the problem remains, and finding a resolution is not...
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Osteoarthritis can increase your risk for social isolation
by American Geriatrics Society When older adults become lonely—a condition health professionals call “social isolation”—their health and well-being can suffer. In fact, there may be a link between being socially isolated and osteoarthritis (arthritis) which causes joint pain and can limit your ability to get around. People who have arthritis often have other health issues...
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Does Drinking Alcohol Cause Joint Pain in Arthritis?
By Dr. Sanchari Sinha Dutta, Ph.D.Reviewed by Dr. Jennifer Logan, MD, MPH Arthritis is a disease of joints, characterized most commonly by joint swelling, stiffness, and pain. Although several studies suggest that drinking alcohol is associated with a lower chance of developing rheumatoid arthritis, there are also numerous studies showing that drinking alcohol is detrimental to...
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Arthritis treatment could provide relief for lichen planus skin rash
by Haley Otman, University of Michigan It’s often difficult to manage patients with this skin inflammation, but new research identifies a target that existing medications are able to address. Constant itchy, painful bumps, scaly arms and legs, and damaged nails make lichen planus an inflammatory skin disease that’s both frustrating and painful for patients trying to keep their quality of life. The...
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