Researchers have found a molecule protects against cartilage deterioration Injecting high levels of the molecule in rats prevented arthritis’ development Molecule replacement therapy could take the place of artificial joint procedures Joint replacements have a long healing process and carry risks of complications Scientists may be one step closer to finding a cure for...
Tag: <span>Arthritis</span>
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Discovery of new T-cell sub type opens window on Rheumatoid Arthritis
Summary: Researchers have scrutinized the immune cells from patients with rheumatoid arthritis, revealing a striking new subset of T-cells that collaborate with other immune cells to drive inflammation in peripheral tissues. A research team led by Scientists from Brigham and Women’s hospital (BWH) has scrutinized the immune cells from patients with rheumatoid arthritis, revealing a...
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Tracking movement of immune cells identifies key first steps in inflammatory arthritis
Identification of molecule required for immune cells to enter joint could lead to new treatment approaches In the image on the left, many green-labeled neutrophils carrying the C5a receptor have moved out from the grey blood vessel into the joint of a mouse in which inflammatory arthritis has been induced. In an animal lacking expression...
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Is this why women are more likely to get arthritis? Scientists have identified a ‘master switch’ gene that causes their immune system to attack itself
Some 8 out of 10 cases of autoimmune diseases are believed to affect women Researchers have pinpointed the key gene that controls their immune system Called VGLL3 – it regulates cells and could pave a way for a drug that targets it A ‘master switch’ that makes women more prone to arthritis has been...
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Want to avoid arthritis? Then brush your teeth: Experts say bugs that cause gum infections also trigger the crippling joint pain
An infection can create proteins that cause the immune system to malfunction In patients with rheumatoid arthritis, this leads to inflammation and joint pain However, this process was also apparent in sample of patients with gum disease Brushing your teeth could prevent arthritis, new research suggests. Bugs known to cause gum infections also trigger...