The CHILDhood Asthma Risk Tool (CHART) can identify children at high risk for asthma at as early as 3 years of age, according to a study published online Oct. 6 in JAMA Network Open. Myrtha E. Reyna, from the Hospital for Sick Children in Toronto, and colleagues developed and evaluated the use of a symptom-based screening...
by NYU Langone Health Credit: Pixabay/CC0 Public Domain Blocking the action of calcium signals in immune cells suppresses the most common form of asthma, but without compromising the body’s defenses against flu viruses, a new study finds. Led by researchers at NYU Grossman School of Medicine, experiments showed that removing the gene for a calcium channel—specifically...
UNIVERSITY HOSPITALS CLEVELAND MEDICAL CENTER CLEVELAND–Many therapeutics for asthma and other obstructive lung diseases target the β2-adrenergic receptor (β2AR), a G protein-coupled receptor (GPCR) that rapidly supports airway relaxation when stimulated. Yet, overuse of these agents is associated with adverse health outcomes, including death, which has limited their utility as frontline therapies. Now, a...
by Josh Barney, University of Virginia Credit: Emily Faith Morgan/University of Virginia A medication used to treat asthma and eczema can improve survival rates for patients with moderate to severe COVID-19, a clinical trial conducted at UVA Health suggests. UVA is the first to test this novel and promising approach to COVID-19 treatment. The study centered...
by Aston University Credit: Pixabay/CC0 Public Domain A possible way to tackle one of the underlying causes of asthma has been developed by researchers from Aston University and Imperial College London. In tests in mice, the researchers were able to virtually eliminate asthmatic symptoms within two weeks and return their airways to near normal. Just under...
by Edith Cowan University Credit: Pixabay/CC0 Public Domain New research led by Edith Cowan University has made an important discovery that could lead to more effective treatments for the world’s 262 million asthma sufferers. A study led by Dr. Stacey Reinke (ECU) and Dr. Craig Wheelock (Karolinska Institute, Sweden) found severe asthmatics have a distinct biochemical...
by Robert H. Shmerling, Harvard University While rainstorms improve conditions for those with allergies or asthma, a new study finds that thunderstorms can aggravate symptoms. Credit: Michael D./Unsplash It’s an old line: “Everyone complains about the weather but no one is doing anything about it.” But if you’re a person with bad allergies or asthma, stormy...
by Amy Chan, The Conversation Digital technologies can help, but they may not be for everyone and some may work better than others. Credit: Shutterstock Modern medical science has made remarkable progress in the treatment of asthma. Inhalers containing steroids are particularly effective in preventing an asthma attack. But getting people to take these preventive medicines long-term...
by Delthia Ricks, Medical Xpress LPS triggers common and distinct responses in human and murine lung tissues and drives systemic responses. (A) Common OSM-dependent, LPS-induced differentially expressed genes (DEG) are shown in human PCLS after 4 hours and mouse lung after 4 hours. (B) Serum cytokines and chemokines were measured in recipient C57BL/6 Osm–/– or...
If you’re wondering whether your child may have asthma, there are some tell-tale signs to look for, an expert says. Asthma is the most common chronic respiratory disease in children and affects more than 6 million U.S. children. Despite being common, diagnosing asthma in children can be difficult because “there is no one-size-fits-all set of symptoms,”...
