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Re­search­ers dis­cover a novel gene in­volved in primary lymph­ed­ema
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Re­search­ers dis­cover a novel gene in­volved in primary lymph­ed­ema

by  University of Helsinki A new model of ANGPT2-mediated TIE2 and TIE1 clustering and activation at atomic resolution. Credit: VM Leppanen et al., Sci. Transl. Med. 12, eaax8013 (2020) The Human Molecular Genetics laboratory of the de Duve Institute (UCLouvain), headed by Professor Miikka Vikkula, recently identified mutations in a novel gene, ANGPT2, responsible for primary lymphedema....