MICHIGAN MEDICINE – UNIVERSITY OF MICHIGAN A team of researchers has found disrupting the interaction between cancer cells and certain immune cells is more effective at killing cancer cells than current immunotherapy treatments. The findings, which include studies in cell lines and animal models, appeared in JCI Insight and focus on a protein called CD6 as a target for a...
Tag: <span>autoimmune diseases</span>
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Immune receptor protein could hold key to treatment of autoimmune diseases
by Tokyo University of Science Credit: CC0 Public Domain Autoimmune diseases are typically caused when the immune system, whose purpose is to deal with foreign threats to the body, incorrectly recognizes the body’s own proteins and cells as threats and activates immune cells to attack them. In the case of rheumatoid arthritis, a well-known autoimmune disease,...
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Immune receptor protein could hold key to treatment of autoimmune diseases
TOKYO UNIVERSITY OF SCIENCE CREDIT: TOKYO UNIVERSITY OF SCIENCE Autoimmune diseases are typically caused when the immune system, whose purpose is to deal with foreign threats to the body, incorrectly recognizes the body’s own proteins and cells as threats and activates immune cells to attack them. In the case of rheumatoid arthritis, a well-known autoimmune...
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Why gut bacteria are becoming key suspects in autoimmune diseases
What causes the immune system to err in this way is not clear, but a growing body of research is looking at the trillions of microbes that share our bodies, known collectively as the microbiome, for an answer. Studies of twins indicate that lifestyle, or environmental, factors can play a large role in autoimmune diseases. Researchers found that...
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Ginger root shows promise in treating certain autoimmune diseases
by John Anderer ANN ARBOR, Mich. — Herbal medicine and science don’t always overlap, but a new study finds ginger root may be an effective supplemental treatment option for certain autoimmune diseases. Researchers from the University of Michigan report the main bioactive ingredient in ginger (6-gingerol) therapeutically counters the mechanism responsible for some autoimmune diseases in mice. Researchers focused...
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A new approach to study autoimmune diseases
by Indiana Biosciences Research Institute Venn diagrams of risk genes expressed in the target tissues of the fourautoimmune diseases (type 1 diabetes, systemic lupus erythematosus, multiple sclerosis, and rheumatoid arthritis) shows shared candidate genes among them. Credit: Indiana Biosciences Research Institute A team of researchers led by the Indiana Biosciences Research Institute Diabetes Center’s Scientific Director Decio L. Eizirik, MD, Ph.D., has found...
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Study identifies key enzyme for development of autoimmune diseases
FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO IMAGE: IT INCREASES CNS AUTOIMMUNE INFLAMMATION. THE CONFOCAL IMAGE DISPLAYS PKM2 EXPRESSION (IN RED) WITHIN THE INFLAMMATORY CELL INFILTRATE IN THE SPINAL CORD OF MICE SUBJECTED TO EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS. Scientists affiliated with the Center for Research on Inflammatory Diseases, hosted by the University of...
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Targeting the treatment of autoimmune diseases
CHARITÉ – UNIVERSITÄTSMEDIZIN BERLIN A team of researchers from Charité – Universitätsmedizin Berlin and the Deutsches Rheuma-Forschungszentrum (DRFZ) Berlin, a Leibniz Institute, have successfully treated two patients with the autoimmune disease systemic lupus erythematosus. Using daratumumab, a monoclonal antibody which targets specific immune cells known as plasma cells, the researchers were able to modulate the abnormal immunological memory processes...
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Study finds molecule in lymphatic system implicated in autoimmune diseases
HOSPITAL FOR SPECIAL SURGERY (New York City. March 20, 2020.) A study by investigators at Hospital for Special Surgery (HSS) has discovered a molecule in the lymphatic system that has the potential to play a role in autoimmune disease. The study, “Lymph node stromal CCL2 limits antibody responses,” was published online today in the journal...
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Insider attacks: Purdue developing new treatment options for millions with autoimmune diseases
Living with an autoimmune disease can feel like an insider is attacking your body. An estimated 24 million people in the United States are affected by autoimmune diseases, a group of diseases in which the person’s immune system attacks part of the person’s own body. Credit: CC0 Public Domain Now, Purdue University researchers have developed...