by Osaka University Credit: Cell Genomics (2024). DOI: 10.1016/j.xgen.2023.100473Much like ripples on the water can betray powerful currents below the surface, small changes in our bodies can sometimes be an indicator of a serious condition. Now, researchers from Japan say that cells in the blood may provide telltale signs of important immune dysfunction. In a study...
by Swansea University Graphical abstract. Credit: Cell Metabolism (2023). DOI: 10.1016/j.cmet.2023.05.001 Swansea University researchers have found that a drug commonly used to treat type 2 diabetes can potentially be used in the treatment of autoimmune disorders. Academics at the University’s Faculty of Medicine, Health and Life Science have found that the drug, canagliflozin (also known as Invokana), could...
by Jonathan Deutschman, Johns Hopkins University Graphical abstract. Credit: Cell Reports (2022). DOI: 10.1016/j.celrep.2022.111478 Autoimmune diseases such as rheumatoid arthritis and multiple sclerosis happen when the immune system is inadvertently activated, mistakenly attacking the body’s tissues and organs. Though it is known that genetics play a role in the development of these disorders, prevention and treatment approaches...
by KU Leuven Credit: Pixabay/CC0 Public Domain About 10% of the population in high income regions like Europe and the United States has been diagnosed with one or multiple autoimmune disorders. Examples are rheumatoid arthritis, psoriasis, systemic sclerosis, lupus erythematosus and type I diabetes. Although earlier research has suggested associations between some of these disorders...
by Bob Yirka , Medical Xpress RNA edQTL map in human tissues. Credit: Nature (2022). DOI: 10.1038/s41586-022-05052-x A team of researchers at Stanford University, working with two colleagues from Fudan University and another from the Broad Institute of MIT and Harvard, has found evidence suggesting that genetic variants that dampen A-to-I RNA editing can be associated with...
January 24, 2022 8.31am EST Author Deborah FullerProfessor of Microbiology, School of Medicine, University of Washington The two most successful coronavirus vaccines developed in the U.S. – the Pfizer and Moderna vaccines – are both mRNA vaccines. The idea of using genetic material to produce an immune response has opened up a world of research...
by The Scripps Research Institute Kendall Nettles, Ph.D., a molecular biologist at Scripps Research, Florida, collaborated with experts in many disciplines to systematically improve the safety of glucocorticoids. Credit: Scripps Research A collaboration led by Scripps Research has developed a way to separate the beneficial anti-inflammatory properties of a group of steroids called glucocorticoids from some of their unwanted side-effects, through an...
One of the most compelling hypotheses in scientific research today is the growing belief that psychiatric disorders are potentially related to immune system irregularities. A team from King’s College London has added substantial weight to that idea with a massive meta-analysis confirming that people with autoimmune disorders are consistently more likely to develop psychotic disorders. A study...
A new study in CMAJ (Canadian Medical Association Journal) found no increased risk of autoimmune disorders in girls who received quadrivalent human papillomavirus (HPV4) vaccination, adding to the body of evidence for the safety of the vaccine. Electron micrograph of a negatively stained human papilloma virus (HPV) which occurs in human warts. Human papillomavirus is the most...
Many people associate the word “bacteria” with something dirty and disgusting. Dr. Pere Santamaria disagrees. Called the microbiome, the bacteria in our bodies have all kinds of positive effects on our health, Santamaria says. “The bacteria we have in our gut actually have many beneficial functions. They help in our digestion, prevent infection by pathogens...
