Tag: <span>autoimmune myopathy</span>

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PCSK9 inhibitors to lower cholesterol in patients with statin-associated autoimmune myopathy

Beyond its toxic effect, statin use has been associated with a rare but potentially severe and disabling type of muscle disease known as statin-associated autoimmune myopathy. Its distinguishing features are the persistence after withdrawal of statins and its association with antibodies against 3-hydroxy-3methylglutaryl coenzyme A reductase (HMGCR). Management usually requires steroids and other immunosuppressive therapies....