This news or article is intended for readers with certain scientific or professional knowledge in the field. Like finding that needle in the haystack every time, your T cells manage what seems like an improbable task: quickly finding a few invaders among the many imposters in your body to trigger its immune response. T cells...
o defend the body, the immune system makes proteins known as antibodies that latch onto the perceived threat, be it HIV, the new coronavirus or, as is the case in autoimmune disease, part of the body itself. In a new proof-of-concept study in ACS Sensors, researchers describe a new system for detecting antibodies within a...
Parasitic worms could offer a new treatment hope for patients suffering from the autoimmune disease multiple sclerosis, according to experts from the University of Nottingham. The findings of the research, published in the journal JAMA Neurology, show that infecting MS patients with a safe dose of the hookworm parasite Necator americanus induces immunoregulatory responses and...
An antibody appears to make a big difference between multiple sclerosis and other disorders affecting the protective myelin sheath around nerve fibres, report Tohoku University scientists and colleagues in the journal Brain. The finding suggests that some of these ‘inflammatory demyelinating diseases’ belong to a different category than multiple sclerosis, and should be treated according...
Scientists from the Antibody and Vaccine group at the University of Southampton have discovered a way to transform antibody drugs previously developed to treat autoimmunity into antibodies with powerful anti-cancer activity through a simple molecular “switch”. This work, published in the journal Cancer Cell, focuses on a molecule called CD40 which is present on the...
Two in 10,000 people are at risk of serious sight loss from a form of eye inflammation known as uveitis. A new clinical research study, led by the University of Bristol and University Hospitals Bristol and Weston NHS Foundation Trust (UHBW), will evaluate a drug combination treatment for the eye disease thanks to the funding...
by Perelman School of Medicine at the University of Pennsylvania When Castleman Disease patients have a flare of their symptoms, they experience a cytokine storm inside their bodies—a hyper-response from the immune system that can cause a fever, organ failure, and even death. Now researchers at the Perelman School of Medicine at the University of...
by Karolinska Institutet According to many observations, certain virus infections may play a part in the autoimmune attack that leads to type 1 diabetes. Researchers at Karolinska Institutet in Sweden and their Finnish colleagues have now produced a vaccine for these viruses in the hope that it could provide protection against the disease. The study...
by Particle Could autoimmune and allergic conditions like Crohn’s disease, multiple sclerosis or type 1 diabetes one day be treated with microbes in your gut? Inside your gut is a collective of bacteria, fungi and viruses known as the gut microbiota. Amazingly, they start to develop immediately after we’re born. With our mother’s bacteria quickly...
More than 50 million Americans are affected by an autoimmune disease, with women at an increased risk for developing one. “Autoimmune conditions can be debilitating for patients,” says Dinesh Khanna, M.D., M.Sc., a professor of rheumatology and the director of the Michigan Medicine Scleroderma Program. “As a National Institutes of Health Autoimmunity Center of Excellence site, we have the opportunity at Michigan Medicine to...
