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Scientists map how ayahuasca affects fear circuits in comprehensive review

New analysis synthesizes decade of research on psychedelic brew’s effects on anxiety and trauma responsesReports and Proceedings Genomic Press image:  Plasticity-promoting mechanisms triggered by dimethyltryptamine (DMT) and β-carboline (BC). (A) DMT and BC-induced increase in cortical plasticity are linked to enhanced BDNF levels, although this might result from activation of different receptors. (B) Increased hippocampal...

Is ayahuasca safe? New study tallies adverse events
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Is ayahuasca safe? New study tallies adverse events

by Public Library of Science Preparation of ayahuasca (from B. caapi and P. viridis). Credit: Daniel Perkins, CC-BY 4.0 (creativecommons.org/licenses/by/4.0/) There is a high rate of adverse physical effects and challenging psychological effects from using the plant-based psychoactive ayahuasca, though they are generally not severe, according to a new study by Daniel Perkins of University...