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A broad-spectrum synthetic antibiotic that does not evoke bacterial resistance
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A broad-spectrum synthetic antibiotic that does not evoke bacterial resistance

by Shelly Leachman, University of California – Santa Barbara Conjugated oligoelectrolytes (COEs) and comparative bactericidal activity and mammalian cell cytotoxicity. a, COEs share a modular structure that spontaneously integrates into the bacterial membrane. b and c, COE structural modules are depicted by colored boxes. The intercalation into phospholipid bilayers is driven by the hydrophobic center...