Findings could pave the way for more personalized treatments for cardiovascular diseasePeer-Reviewed Publication NIH/National Heart, Lung and Blood Institute National Institute of Health (NIH) scientists have made a significant breakthrough in understanding how “bad” cholesterol, known as low-density lipoprotein-cholesterol or LDL-C, builds up in the body. The researchers were able to show for the first time...
Tag: <span>bad cholesterol</span>
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‘Bad’ cholesterol gene silenced without altering the DNA sequence
By Paul McClure Epigenetic editing has been used to silence a cholesterol-regulating gene in miceAI-generated by DALL-E By silencing the gene responsible for regulating ‘bad’ cholesterol without altering the primary DNA sequence, researchers have shown that it’s possible to use epigenetic editing to treat diseases rather than conventional DNA-breaking gene editing technology, which risks unintended effects....
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Haywire T cells attack protein in “bad” cholesterol
by La Jolla Institute for Immunology T cells may drive inflammation as dangerous plaques build up in the cardiovascular system. Image from La Jolla Institute for Immunology. Credit: La Jolla Institute for Immunology Preventing atherosclerosis, the underlying cause of heart disease, means scientists need to understand how immune cells drive inflammation in the arteries. The challenge is that the T cells involved...
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One avocado a day helps lower ‘bad’ cholesterol for heart healthy benefits
PENN STATE UNIVERSITY PARK, Pa. — Move over, apples — new research from Penn State suggests that eating one avocado a day may help keep “bad cholesterol” at bay. According to the researchers, bad cholesterol can refer to both oxidized low-density lipoprotein (LDL) and small, dense LDL particles. In a randomized, controlled feeding study, the...
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Researchers have warned statins offer no protection to millions of people
‘No evidence’ having high levels of bad cholesterol causes heart disease, claim 17 cardiologists as they call on doctors to ‘abandon’ statins Researchers have warned statins to offer no protection to millions of people The findings add to the ever-growing row over the cholesterol-busting pills High levels of LDL-C has been considered a major cause of...