Credit: Unsplash/CC0 Public Domain A top California health plan is set to offer one of the world’s biggest-selling drugs for free in a bid to show the medicine can reach Americans affordably without going through the middlemen that typically control its flow. Blue Shield of California struck an unusual deal to buy a lower-cost version...
Tag: <span>Basic research</span>
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Phage therapy: Researchers sharpen another arrow in the quiver against antibiotic resistance
By Deborah Balthazar At the University of Pittsburgh, testing to pick the best phage to fight infection-causing bacteria. UNIVERSITY OF PITTSBURGH Lynn Cole was in a never-ending cycle of getting recurrent blood infections. And no antibiotic drugs managed to kill off her zombie-like bacteria.“It just got so frustrating over the years because we couldn’t find the...
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Basic research opens up new therapeutic opportunities for fighting leukemia
by University of Veterinary Medicine—Vienna Genome-wide CRISPR/Cas9-based loss-of-function screen identifies genetic dependencies of STAT3Y640F-driven cells a) Schematic illustration of a competitive proliferation assay. b) Competitive proliferation assays of clonal Cas9-expressing STATY640F-driven HPC7 or c) clonal Cas9-HPC7 empty vector cells expressing IRF670 and sgRNAs targeting either Myb (positive control) or the Rosa26 locus (negative control). d)...