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New research may hold key to better treatments for aggressive brain cancer
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New research may hold key to better treatments for aggressive brain cancer

by Spectrum Health Prakash Chinnaiyan, M.D., a physician scientist in the Department of Radiation Oncology at Corewell Health in Southeast, Mich. Credit: Elizabeth Debeliso, Corewell Health For decades, researchers have marveled at the ability of glioblastoma, a particularly aggressive brain cancer, to turn off a patient’s cancer-fighting immune cells, thereby allowing tumors to grow freely. This remains...

New way to track peripheral artery disease aids quest for better treatments
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New way to track peripheral artery disease aids quest for better treatments

UNIVERSITY OF VIRGINIA HEALTH SYSTEM IMAGE: UVA HEALTH’S CHRISTOPHER KRAMER, MD, AND COLLABORATORS HAVE DEVELOPED A NEW WAY TO TRACK PERIPHERAL ARTERY DISEASE. CREDIT: DAN ADDISON | UNIVERSITY OF VIRGINIA COMMUNICATIONS Cardiovascular experts at UVA Health have found a new way to track peripheral artery disease (PAD), a serious medical condition involving atherosclerosis in the...

New research may pave the way to better treatments for Crohn’s disease
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New research may pave the way to better treatments for Crohn’s disease

by Stony Brook University IL-17A acts on unique cell types to regulate intestinal function. Under normal conditions, IL-17A acts on stem cells to promote their differentiation into secretory epithelial cells. This visual depicts that during colitis, IL-17A acts on secretory cells to mitigate the disease’s inflammatory effects. Credit: Pawan Kumar A paper published this week...

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Human parasite’s daily rhythms could be targeted for better treatments

The parasitic worm that causes the neglected tropical disease, schistosomiasis, has daily rhythms in gene expression, including genes that could be targeted in drug development. For the first time, the worm that causes schistosomiasis has been shown to have a daily rhythm that impacts which genes are switched on at different times. The new research,...