by Brittany Phillips, University of North Carolina at Chapel Hill School of Medicine Conclusions. Credit: Pediatric Allergy and Immunology (2024). DOI: 10.1111/pai.14267 Metabolites—small molecules within cells, biofluids, tissues or organisms—play an integral role in various diseases, and studying the many metabolites (metabolomics) can teach us how the body works in ways that help researchers develop new treatments, especially...
Tag: <span>bile acid</span>
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Bile acid breakthrough: Researchers team up for microbiome discoveries
by Michigan State University A 3D rendering of the enzyme bile salt hydrolase, or BSH. In a testament to land-grant collaboration, researchers at Michigan State University and Pennsylvania State University teamed up to reveal the different critical roles BSH plays in our microbiome, leading to two papers published simultaneously in Nature. Credit: M. Rossocha et al...
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Novel approach to treat and prevent type 2 diabetes using bile acid composition
by National University of Singapore Credit: Pixabay/CC0 Public Domain Bile acids, a digestive juice, may hold the key to a new way of treating and preventing type 2 diabetes. Bile acids do more than just helping with food digestion: They also act as signaling molecules and control various body functions, including the regulation of blood...
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Interruption of bile acid uptake by liver cells after paracetamol overdose mitigates liver damage
by Anne Rommel, Leibniz-Institut für Arbeitsforschung an der TU Dortmund Graphical abstract. Credit: Journal of Hepatology (2022). DOI: 10.1016/j.jhep.2022.01.020 Poisoning with paracetamol (acetaminophen—APAP) is a common cause of liver failure. However, not all the correlations that lead to liver damage from APAP are yet known. Especially the role of bile acids is unclear. The Leibniz Research Center...