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Bile acid breakthrough: Researchers team up for microbiome discoveries
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Bile acid breakthrough: Researchers team up for microbiome discoveries

by Michigan State University A 3D rendering of the enzyme bile salt hydrolase, or BSH. In a testament to land-grant collaboration, researchers at Michigan State University and Pennsylvania State University teamed up to reveal the different critical roles BSH plays in our microbiome, leading to two papers published simultaneously in Nature. Credit: M. Rossocha et al...

Interruption of bile acid uptake by liver cells after paracetamol overdose mitigates liver damage
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Interruption of bile acid uptake by liver cells after paracetamol overdose mitigates liver damage

by Anne Rommel, Leibniz-Institut für Arbeitsforschung an der TU Dortmund  Graphical abstract. Credit: Journal of Hepatology (2022). DOI: 10.1016/j.jhep.2022.01.020 Poisoning with paracetamol (acetaminophen—APAP) is a common cause of liver failure. However, not all the correlations that lead to liver damage from APAP are yet known. Especially the role of bile acids is unclear. The Leibniz Research Center...