by Julie Cunningham, Massachusetts General Hospital Credit: CC0 Public Domain A skin pigmentation mechanism that can darken the color of human skin as a natural defense against ultraviolet (UV)-associated cancers have been discovered by scientists at Massachusetts General Hospital (MGH). Mediating the biological process is an enzyme, NNT, which plays a key role in the production...
Tag: <span>biochemical pathway</span>
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Researchers discover biochemical pathway that protects cells from ferroptosis
by H. Lee Moffitt Cancer Center & Research Institute Credit: Pixabay/CC0 Public Domain The hallmarks of cancer include rapid cell reproduction and metabolic activity. But these processes also lead to increased cellular stress and oxidation, and the risk of cell death. To circumvent these negative consequences of supercharged growth, cancer cells stimulate pathways to reduce oxidative stress and...