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T-cell biofactories find, fight disease in one fell swoop

NIBIB-funded researchers have transformed T cells into drug factories engineered to find cells carrying specific diseases in the body—and then produce therapeutic proteins localized to the diseased cells. Senior author Parijat Bhatnagar, Ph.D., director of cell-based medicine at the SRI International Center for Chemical Biology, Menlo Park, California, and his colleagues engineered the T-cell “biofactories”...