Many different types of medications help treat Crohn’s disease, including a group of drugs known as biologics. Doctors often prescribe them for people with moderate to severe symptoms caused by Crohn’s disease. Crohn’s disease is a chronic inflammatory bowel disease (IBD) that causes episodic inflammation, swelling, and irritation within the digestive tract. There is no...
Tag: <span>Biologic Drugs</span>
Post
Advanced microscopy reveals unusual DNA structure
Sandia scientist pushes technology’s limits to see fundamental feature of stretched S-DNA An advanced imaging technique reveals new structural details of S-DNA, ladder-like DNA that forms when the molecule experiences extreme tension. This work conducted at Sandia National Laboratories and Vrije University in the Netherlands provides the first experimental evidence that S-DNA contains highly tilted...
Post
Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs
Highlights Stem cells were rewired via genome engineering to combat inflammation Cells were used to engineer tissues that self-regulate biologic drug production Autoregulated therapy protected tissues from cytokines that drive chronic diseases This approach can form the basis of a cellular vaccine for inflammatory diseases Summary Chronic inflammatory diseases such as arthritis are characterized by...