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How immune cells activate the killer mode
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How immune cells activate the killer mode

UNIVERSITY OF FREIBURG FROM LEFT: SUSANA MINGUET, WOLFGANG SCHAMEL, FREDERIKE HARTL. view more CREDIT: PHOTO: LAURENZ HERR, ANJA SCHWÄBLE Unraveling a key motif: The T lymphocytes of the immune system work to destroy infected cells or cancer cells. To do so, they have to identify the threat: Molecules perceived as foreign – so-called antigens –...

Chemical offers new hope of finding treatments for neglected tropical diseases
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Chemical offers new hope of finding treatments for neglected tropical diseases

by University of York Targeting the Trypanosoma brucei cell cycle: the target represents the compound AB1, and (the dart) its phenotype showed as a parasite with cell cycle defects. Credit: Manuel Saldivia and Andrés Sánchez Scientists say they are a step closer to developing a drug to kill the trypanosome parasite that causes human African...

New molecular tool precisely edits mitochondrial DNA
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New molecular tool precisely edits mitochondrial DNA

UW microbiologists discovered a bacterial toxin that, when engineered, is a key part of a gene editor that can make single-base changes in human mitochondria. The genome in mitochondria — the cell’s energy-producing organelles — is involved in disease and key biological functions, and the ability to precisely alter this DNA would allow scientists to...

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Blood iron levels could be key to slowing ageing, gene study shows

UNIVERSITY OF EDINBURGH Genes linked to ageing that could help explain why some people age at different rates to others have been identified by scientists. The international study using genetic data from more than a million people suggests that maintaining healthy levels of iron in the blood could be a key to ageing better and...

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Is what I see, what I imagine? Study finds neural overlap between vision and imagination

by Catherine Bridges, Medical University of South Carolina An ibis as “seen” by a machine, 2015. This processed image, which is based on a photograph by Dr. Zachi Evenor, is courtesy of software engineer Guenther Noack, 2015, and is reproduced from Wikimedia Commons (CC BY 4.0). Credit: Dr. Guenther Noack, 2015, reproduced from Wikimedia Commons...

Lung cancer proteome builds on genetic findings to reveal therapeutic strategies
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Lung cancer proteome builds on genetic findings to reveal therapeutic strategies

by Tom Ulrich, Broad Institute of MIT and Harvard Lung cancer is the most commonly diagnosed cancer worldwide and the leading cause of cancer-related deaths, killing more per year than breast, colon, and prostate cancers combined. Over the years, studies of the lung cancer genome have fueled the development of drug therapies that target mutations...

Lung cancer in non-smokers likely to respond differently to treatment
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Lung cancer in non-smokers likely to respond differently to treatment

by Institute of Cancer Research Lung cancer in non-smokers is a diverse and distinct disease from that in smokers, and is likely to respond differently to targeted treatments, a major new study shows. Scientists studied a population in Taiwan with high rates of lung cancer among non-smokers—and found a range of genetic changes which varied...