by University of California, Los Angeles “As pregnancy complications continue to rise worldwide, there have been increasing efforts to study with urgency the first-trimester as a window of opportunity for early identification and prediction of GDM, and the optimal point to take action to prevent maternal disease,” said Dr. Sherin Devaskar, lead author of the study....
by Medical College of Wisconsin Ovary. Credit: Public Domain Scientists at the Medical College of Wisconsin (MCW) Cancer Center and an international team of collaborators have identified a new mechanism of cMYC regulation in ovarian cancer. Although the cMYC gene aberration is present in nearly half of all cancer patients, it’s been a challenge to use cMYC as a therapeutic target due to its ‘undruggable’ protein structure. The study...
by Memorial Sloan Kettering Cancer Center Scanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAID In recent years, immune-based treatments for cancer have buoyed the hopes of doctors and patients alike. Drugs called immune checkpoint inhibitors have provided lifesaving benefits to a...
by Sanford Burnham Prebys Medical Discovery Institute Functional magnetic resonance imaging (fMRI) and other brain imaging technologies allow for the study of differences in brain activity in people diagnosed with schizophrenia. The image shows two levels of the brain, with areas that were more active in healthy controls than in schizophrenia patients shown in orange, during...
by Queen Mary, University of London Pancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer Institute Researchers from Queen Mary University of London have identified a protein that could be used to aid in the diagnosis of pancreatic cancer. Findings from the new study suggest that a protein called pentraxin 3...
by Walter and Eliza Hall Institute Crypts and buds in the small intestine and colon. Credit: Dr. Maree Faux, WEHI. A biomarker in the blood of patients with bowel cancer may provide valuable insight into the risk of cancer relapse after surgery and the effectiveness of chemotherapy. Research published in PLOS Medicine found circulating tumor DNA...
UNIVERSITY OF ARIZONA HEALTH SCIENCES A promising new biomarker that appears in patients before stomach cancer develops may help with early detection of the disease and improve patient response to therapy, according to findings in a study led by University of Arizona Health Sciences researchers. The biomarker can be detected through a simple blood test, saving...
UNIVERSITY OF SOUTH AUSTRALIA Using new state-of-the-art imaging techniques to identify signs of osteoarthritis (OA), UniSA scientists are learning more about changes at the molecular level which indicate the severity of cartilage damage. A study led by PhD student Olivia Lee and her supervisor Associate Professor Paul Anderson using mass spectrometry imaging (MSI) has mapped...
By Rich Haridy, September 21, 2020 A protein associated with neurodegeneration, previously detected in blood samples, has now been found in eye fluid A protein, previously found to be an effective blood-based biomarker of neurodegenerative diseases such as Alzheimer’s, has for the first time been detected in the eye. The discovery lays the foundation for...
by The Korea Advanced Institute of Science and Technology (KAIST) Figure. Low glucocorticoid receptor (GR) expression led to excessive inflammation and lung damage by neutrophils through enhancing the expression of CXCL8 and other cytokines. Credit: The Korea Advanced Institute of Science and Technology (KAIST) KAIST researchers have identified key markers that could help pinpoint patients who...
