Tag: <span>biomarker</span>

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Loss of lipid-regulating gene fuels prostate cancer spread
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Loss of lipid-regulating gene fuels prostate cancer spread

JOHNS HOPKINS MEDICINE ANCER CELLS GOBBLE UP LIPIDS. PROSTATE CELLS ARE STAINED WITH OIL-RED O TO DETECT LIPID DROPLETS. OUR WORK SHOWS THAT REDISTRIBUTION OF LIPIDS FROM PROSTATE CANCER MICROENVIRONMENT TRIGGERS INFLAMMATION AND… view more CREDIT: NICK (JIN-YIH) LOW Johns Hopkins Kimmel Cancer Centerresearchers from the Department of Radiation Oncology and Molecular Radiation Sciences identified...

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Biomarker for Parkinson’s disease may originate in the gut

by Lori Dajose, California Institute of Technology Parkinson’s disease (PD) is a debilitating neurodegenerative disorder, impairing the motor functions of millions of elderly people worldwide. Often, people with PD will experience disturbances in gastrointestinal function, such as constipation, years before motor symptoms set in. Postmortem examinations of the brains of people with PD have shown...

New biomarker could better predict diabetic kidney disease
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New biomarker could better predict diabetic kidney disease

by Tyrel Linkhorn, University of Toledo Clinicians may soon have a better way to predict which of their diabetic patients are most likely to develop kidney disease, allowing for earlier interventions that keep patients off lifelong dialysis or transplant waiting lists. In a study led by Dr. Rujun Gong, professor and director of kidney research...

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Biomarker blood test could reveal high risk heart patients in need of treatment

UT SOUTHWESTERN MEDICAL CENTER DALLAS – Nov. 11, 2019 – Without occasionally looking under the hood, it’s difficult to predict whether expensive car repairs lie ahead. In a similar way, preventive cardiologists are looking for ways to detect early stage heart disease in people who aren’t currently in treatment. Preventive cardiology researchers at UT Southwestern Medical Center believe...

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Researchers identify biomarker to predict if someone infected with malaria will get sick

by  Cell Press Immunological signatures can predict whether malaria-infected children will develop fever or other symptoms, suggests a study publishing September 3 in the journal Immunity. Surprisingly, activation of the well-known tumor-suppressor protein p53 is associated with enhanced protection against malaria fever—and increasing p53 in human immune cells and in mice results in a decrease in...

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New biomarker panel could accelerate autism diagnoses

About 17 percent of kids with autism identified with metabolic blood test UNIVERSITY OF CALIFORNIA – DAVIS HEALTH SYSTEM Investigators at the UC Davis MIND Institute and NeuroPointDX, a division of Stemina Biomarker Discovery, have identified a group of blood metabolites that could help detect some children with autism spectrum disorder (ASD). Part of the...

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T-Cell Biomarker Predicts Response to CAR T-Cell Therapy in Patients With CLL

Chimeric antigen receptor (CAR) T-cell therapy has been hailed as one of the great advances in oncology care, but not all patients will respond. This is particularly the case with relapsed/refractory chronic lymphocytic leukemia (CLL), where durable antitumor complete responses have been observed in only 26% of patients,  in contrast to the greater than 90%...

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Discovery of new biomarker could provide personalized treatment options for bladder cancer

Mount Sinai researchers use data science and genomics to help determine best treatment options for specific bladder cancers THE MOUNT SINAI HOSPITAL / MOUNT SINAI SCHOOL OF MEDICINE A potential new target for treatment has been identified in an aggressive form of bladder cancer, Mount Sinai researchers report in a recent study. Bladder cancers are...