by Technion – Israel Institute of Technology Graphical abstract. Credit: Cancer Cell (2024). DOI: 10.1016/j.ccell.2023.12.005Researchers at the Technion’s Ruth and Bruce Rappaport Faculty of Medicine and the Rappaport Family Institute for Research in the Medical Sciences have discovered a subset of blood cells that predict the success of immunotherapy treatment. These findings are expected to streamline...
by Werner Siefer, Paul Scherrer Institute Overview of our platform to study the chromatin organization of peripheral blood mononuclear cells in a tumor and proton therapy setting. Credit: npj Precision Oncology (2023). DOI: 10.1038/s41698-023-00484-8 The ability to detect a developing tumor at a very early stage and to closely monitor the success or failure of cancer...
by American Gastroenterological Association Credit: Nephron/WikipediaThe American Gastroenterological Association (AGA) has released a new evidence-based guideline recommending the use of blood and stool-based biomarkers to help manage Crohn’s disease, a type of inflammatory bowel disease (IBD). IBD is estimated to affect 2.74 million people in the U.S. The guideline was published today in Gastroenterology. Biomarkers...
By Ben Coxworth The prototype device, which is currently being commercialized by biotech company Ampera LifeDavid Baillot/UC San Diego Jacobs School of Engineering Because of the logistics and invasive procedures involved, many people put off getting tested for Alzheimer’s and Parkinson’s diseases. Thanks to a new portable device, however, such testing could soon be performed non-invasively...
by Nancy Fliesler, Children’s Hospital Boston Perchloric acid depletion workflow and method validation. (A) Workflow: PerCA plasma proteomic platform. (B) Principal components analysis to identify possible batch effects between phases 1 and 3 (colored in purple, pink, and brown) acquired over a 10-month period. (C) Sample-to-sample correlation of all reference plasma samples from the 44 plates....
by Stephanie Winn, UC Davis Credit: UC Davis Prostate cancer is the second leading cause of death in American men. Understanding the factors that influence patient outcomes is critical for improving treatment and survival rates. Research led by UC Davis Comprehensive Cancer Center reveals a link between bone metabolism biomarkers and survival in men with newly...
by UCLA Engineering Institute for Technology Advancement Deep Learning-Enabled Multiplexed Point-of-Care Sensor using a Paper-Based Fluorescence Vertical Flow Assay. Credit: Ozcan Lab @ UCLA Centralized laboratory testing has been a standard tool for diagnosing common illnesses. However, laboratory-based testing generally requires expensive medical equipment and involves complex operation protocols that can only be completed within a...
by Boston University School of Medicine Partial Least Square regression identifies clusters of proteins that correlate with each tauopathy. Using the partial least square regression analysis, five clusters of ELISA proteins were identified and compared against each tauopathy to determine degree of correlation. Each comparison was a contrast of a single tauopathy against all other...
by University of Gothenburg Credit: Pixabay/CC0 Public Domain In recent years, subcortical small-vessel disease has become an increasingly common cognitive diagnosis. Researchers at University of Gothenburg have now shown that it is possible to identify patients with the disease by combining two biomarkers that are measured in spinal fluid and blood, increasing the potential for...
Researchers led by bioengineers at the University of California San Diego have identified and characterized a previously unrecognized key player in cancer evolution: clusters of mutations occurring at certain regions of the genome. The researchers found that these mutation clusters contribute to the progression of about 10% of human cancers and can be used to predict...
