September 25, 2024 by Mallory Locklear, Yale University A reproducible set of CAPs in the whole-brain rs-fMRI involve recurring mixed representations of canonical resting-state networks. Credit: PLOS Biology (2024). DOI: 10.1371/journal.pbio.3002808A key challenge in the effort to link brain activity with behavior is that brain activity, measured by functional magnetic resonance imaging (fMRI), for instance,...
Tag: <span>biomarkers</span>
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Chinese Medical Journal Pulmonary and Critical Care Medicine study explores biomarkers for pulmonary fibrosis management
News Release 9-Sep-2024 The review explores how biomarkers could revolutionize the diagnosis, prognosis, and treatment of pulmonary fibrosis for enhanced patient outcomes Peer-Reviewed PublicationChinese Medical Journals Publishing House Co., Ltd. image: Biomarkers revolutionize the diagnosis and management of Idiopathic Pulmonary Fibrosis, leading to improved patient outcomes Credit: Yong Zhou of the Tulane University Image Source...
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Study identifies new biomarkers of Alzheimer’s disease
JULY 22, 2024 by Ingrid Fadelli , Medical Xpress Study overview. Credit: Nature Human Behaviour (2024). DOI: 10.1038/s41562-024-01924-6Recent advances in the study of proteomes (i.e., the entire range of proteins expressed by human cells and tissues) have opened new opportunities for identifying the biological markers of specific diseases or mental disorders. This could in turn...
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Predicting immunotherapy success via biomarkers
by Technion – Israel Institute of Technology Graphical abstract. Credit: Cancer Cell (2024). DOI: 10.1016/j.ccell.2023.12.005Researchers at the Technion’s Ruth and Bruce Rappaport Faculty of Medicine and the Rappaport Family Institute for Research in the Medical Sciences have discovered a subset of blood cells that predict the success of immunotherapy treatment. These findings are expected to streamline...
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Enabling early detection of cancer with AI-based chromatin biomarkers
by Werner Siefer, Paul Scherrer Institute Overview of our platform to study the chromatin organization of peripheral blood mononuclear cells in a tumor and proton therapy setting. Credit: npj Precision Oncology (2023). DOI: 10.1038/s41698-023-00484-8 The ability to detect a developing tumor at a very early stage and to closely monitor the success or failure of cancer...
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First comprehensive guideline on using biomarkers for monitoring Crohn’s disease
by American Gastroenterological Association Credit: Nephron/WikipediaThe American Gastroenterological Association (AGA) has released a new evidence-based guideline recommending the use of blood and stool-based biomarkers to help manage Crohn’s disease, a type of inflammatory bowel disease (IBD). IBD is estimated to affect 2.74 million people in the U.S. The guideline was published today in Gastroenterology. Biomarkers...
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Portable device detects Alzheimer’s and Parkinson’s biomarkers on the spot
By Ben Coxworth The prototype device, which is currently being commercialized by biotech company Ampera LifeDavid Baillot/UC San Diego Jacobs School of Engineering Because of the logistics and invasive procedures involved, many people put off getting tested for Alzheimer’s and Parkinson’s diseases. Thanks to a new portable device, however, such testing could soon be performed non-invasively...
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New method enables detection of plasma biomarkers cheaply and at scale
by Nancy Fliesler, Children’s Hospital Boston Perchloric acid depletion workflow and method validation. (A) Workflow: PerCA plasma proteomic platform. (B) Principal components analysis to identify possible batch effects between phases 1 and 3 (colored in purple, pink, and brown) acquired over a 10-month period. (C) Sample-to-sample correlation of all reference plasma samples from the 44 plates....
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Strong link between bone biomarkers and prostate cancer survival
by Stephanie Winn, UC Davis Credit: UC Davis Prostate cancer is the second leading cause of death in American men. Understanding the factors that influence patient outcomes is critical for improving treatment and survival rates. Research led by UC Davis Comprehensive Cancer Center reveals a link between bone metabolism biomarkers and survival in men with newly...
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A rapid and inexpensive paper-based test for multiplexed sensing of biomarkers
by UCLA Engineering Institute for Technology Advancement Deep Learning-Enabled Multiplexed Point-of-Care Sensor using a Paper-Based Fluorescence Vertical Flow Assay. Credit: Ozcan Lab @ UCLA Centralized laboratory testing has been a standard tool for diagnosing common illnesses. However, laboratory-based testing generally requires expensive medical equipment and involves complex operation protocols that can only be completed within a...