by Boston University School of Medicine Partial Least Square regression identifies clusters of proteins that correlate with each tauopathy. Using the partial least square regression analysis, five clusters of ELISA proteins were identified and compared against each tauopathy to determine degree of correlation. Each comparison was a contrast of a single tauopathy against all other...
by University of Gothenburg Credit: Pixabay/CC0 Public Domain In recent years, subcortical small-vessel disease has become an increasingly common cognitive diagnosis. Researchers at University of Gothenburg have now shown that it is possible to identify patients with the disease by combining two biomarkers that are measured in spinal fluid and blood, increasing the potential for...
Researchers led by bioengineers at the University of California San Diego have identified and characterized a previously unrecognized key player in cancer evolution: clusters of mutations occurring at certain regions of the genome. The researchers found that these mutation clusters contribute to the progression of about 10% of human cancers and can be used to predict...
SOUTH URAL STATE UNIVERSITY War veterans have helped scientists of South Ural State University identify biological indicators which signal whether people have a post-traumatic stress disorder or a susceptibility to it. The research results are published in the Journal of Psychiatric Research(Q1) top-rated scientific journal. In their research works on studying post-traumatic stress disorder, the representatives of the SUSU School of Medical...
by Karthika Kaveri Maiappan, Indian Institute of Science A comparison of monocyte and neutrophil phenotype in grade four and grade three gliomas. Credit: Jayashree V Raghavan, created on biorender.com Researchers at the Indian Institute of Science (IISc), along with collaborators, have identified potential blood-based biomarkers to predict disease progression and survival times in those with late-stage brain...
by Swinburne University of Technology Credit: Pixabay/CC0 Public Domain Researchers from the Swinburne Anorexia Nervosa (SWAN) Research Group have discovered what is believed to be the first biomarker for anorexia nervosa. Biomarkers are typically used in the detection and treatment of physical illnesses, but never before have they been used in mental disorders. The challenges of diagnosis Anorexia nervosa...
by National University of Singapore Professor Eric Chan (middle) from the NUS Department of Pharmacy led the research which was conducted in collaboration with the Health Sciences Authority (HSA). The research team included Ms Moy Hooi Yan (extreme left), HSA’s Laboratory Director of the Analytical Toxicology Lab – Drug Abuse Testing, and Dr Wang Ziteng (extreme right), Research Fellow at the NUS...
by University of Eastern Finland Figure 1: Primary quantification revealed no difference between the total sequenced reads and the sequenced reads mapping to miRNAs between experimental groups. (A) miRNA and transfer RNA reads comprised of 50–70% of the total sequenced reads (y-axis) across all samples in the experimental groups (x-axis; naïve n = 4, sham n...
WASHINGTON STATE UNIVERSITY PULLMAN, Wash. – Biomarkers in human sperm have been identified that can indicate a propensity to father children with autism spectrum disorder. These biomarkers are epigenetic, meaning they involve changes to molecular factors that regulate genome activity such as gene expression independent of DNA sequence, and can be passed down to future...
With the help of algorithms, researchers at Karolinska Institutet in Sweden have identified markers that can differentiate between irritant eczema and contact allergy, two skin reactions that look similar but require different treatment. Their findings, which are published in the journal Proceedings of the National Academy of Sciences (PNAS), support the further development of alternative...
