by University College Dublin Credit: Pixabay/CC0 Public Domain The risk of schizophrenia and bipolar disorder may be detectable years before the illnesses begin, according to new research. A University College Dublin led study funded by the Health Research Board has found that 50% of people who developed these mental health disorders had attended specialist child and adolescent...
Bipolar disorder is a mental health condition that can result in extreme shifts in mood. As this may affect how a person thinks, feels, and behaves, it may present challenges that can make it difficult to maintain friendships. Bipolar disorder is a mood disorder that can severely disrupt a person’s life. There are different types of bipolar...
Karolinska Institutet A bottle of lithium capsules. Credit: James Heilman, MD/Wikimedia Commons, CC BY-SA 4.0 Six predictors could help determine the amount of lithium needed to treat patients with bipolar disorder, according to a large study led by researchers at Karolinska Institutet in Sweden. The study, published in the journal The Lancet Psychiatry, also pinpoints genetic markers that...
Lithium’s main treatment for bipolar disorder was approved a half-century ago but didn’t help all patients and has significant side effects. In part, little progress has been made in finding better therapies because scientists don’t fully understand how the condition arises or exactly how lithium improves symptoms when it does work. A genetic study involving...
by Ingrid Fadelli, Medical Xpress Seed points may spread the chromatin hyperacetylation in the nucleus of the nerve cells of the immature brain, resulting in psychiatric disease later in life. Credit: Girdhar et al. The complete set of nucleic acid sequences composing chromosomes in humans, encoded as DNA, is known as the “human genome sequence.”...
by University of New South Wales Credit: Unsplash/CC0 Public Domain A brain imaging study of young people at high risk of developing bipolar disorder has for the first time found evidence of weakening connections between key areas of the brain in late adolescence. Up until now, medical researchers knew that bipolar disorder was associated with reduced communication...
Digitalisation plays a part in everything we do in our daily lives. Mountains of data collected from all our devices are a key ingredient in the digitalisation process. Health apps on our mobile phones, for example, record our unique behavioural and physiological data, and use that data to help us monitor and understand our own...
by Karolinska Institutet Figure 1. Effect sizes (Cohen’s d; top) and significance of group differences (p-value; bottom) between BD patients and HC mapped into brain space. Cortical thickness findings (left) and surface area findings (right) are shown. The Figure displays the overall pattern in the uncorrected raw results. See Figure 3 for findings after multiple comparisons...
by University of Exeter Figure 1: CONSORT diagram of trial recruitment and retention. Credit: DOI: 10.1186/s40345-021-00226-4 Researchers have conducted a new trial to identify how an existing psychological therapy can be adapted to help people cope with and manage frequent Bipolar mood swings. A subgroup of those with bipolar spectrum disorders experiences ongoing mood fluctuations outside of...
by Katie Ann McCarver, University of Iowa Credit: Pixabay/CC0 Public Domain A new study shows that individuals with bipolar disorder who are exposed to significant trauma may be at greater risk for suicide death, suggesting that clinical diagnosis of or genetic predisposition to trauma-related conditions could be important factors to consider in suicide prevention. Suicide is...
