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Researchers identify 20 novel gene associations with bipolar disorder

by  The Mount Sinai Hospital In the largest study of its kind, involving more than 50,000 subjects in 14 countries, researchers at the Icahn School of Medicine at Mount Sinai and more than 200 collaborating institutions have identified 20 new genetic associations with one of the most prevalent and elusive mental illnesses of our time—bipolar disorder. The study is reported in the May...

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Probiotics could help millions of patients suffering from bipolar disorder

About 3 million people in the US are diagnosed every year with bipolar disorder, a psychiatric condition characterized by dramatic shifts in mood from depression to mania. Currently, the standard treatment includes a combination of psychotherapy and prescription medications such as mood stabilizers and antipsychotics. However, an emerging field of research is exploring the use...

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Mutation links bipolar disorder to mitochondrial disease

Mutations in the gene ANT1 may confer a risk for bipolar disorder through a complex interplay between serotonin and mitochondrial signaling in the brain. These two pathways have been separately implicated in bipolar disorder, but the link between levels of the neurotransmitter serotonin and mitochondrial dysfunction had not been established. Researchers at the RIKEN Center for Brain...

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Is it major depression or bipolar disorder? Ask the heart

All test subjects in the study underwent a 15-minute-long electrocardiogram   People suffering from bipolar disorder swing between emotional highs (manic episodes) and severe depression. Perhaps not surprisingly, they’re often mistakenly diagnosed as simply having major depression, which actually requires a different treatment. According to a new study from Illinois’ Loyola University, however, the two...

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