Tag: <span>blood-brain barrier</span>

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New research shows SARS-CoV-2 spike proteins disrupt the blood-brain barrier
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New research shows SARS-CoV-2 spike proteins disrupt the blood-brain barrier

TEMPLE UNIVERSITY HEALTH SYSTEM IMAGE: SERVIO H. RAMIREZ, PHD, PROFESSOR OF PATHOLOGY AND LABORATORY MEDICINE AT THE LEWIS KATZ SCHOOL OF MEDICINE AT TEMPLE UNIVERSITY AND PRINCIPAL INVESTIGATOR ON THE NEW STUDY. (Philadelphia, PA) – Like a key, SARS-CoV-2 – the virus that causes coronavirus disease 2019 (COVID-19) – attaches to specific molecules on the...

Researchers destroy cancer cells with ultrasound treatment
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Researchers destroy cancer cells with ultrasound treatment

An international research team led by Dr. Tali Ilovitsh of the Biomedical Engineering Department at Tel Aviv University developed a noninvasive technology platform for gene delivery into breast cancer cells. The technique combines ultrasound with tumor-targeted microbubbles. Once the ultrasound is activated, the microbubbles explode like smart and targeted warheads, creating holes in cancer cells’...

Diagnosing brain tumors with a blood test
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Diagnosing brain tumors with a blood test

by University Health Network Dr. Daniel De Carvalho and Krembil Brain Institute Medical Director Dr. Gelareh Zadeh collaborated to combine advanced technology with machine learning to develop a highly sensitive and accurate blood test to detect and classify brain cancers. Credit: UHN A simple but highly sensitive blood test has been found to accurately diagnose...

Focused ultrasound opening brain to previously impossible treatments
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Focused ultrasound opening brain to previously impossible treatments

University of Virginia’s School of Medicine and School of Engineering, is using focused soundwaves to overcome the natural ‘blood-brain barrier,’ which protects the brain from harmful pathogens. Credit: Dan Addison | UVA Communications University of Virginia researchers are pioneering the use of focused ultrasound to defy the brain’s protective barrier so that doctors could, at...

APOE4 triggers early breakdowns in the blood-brain barrier
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APOE4 triggers early breakdowns in the blood-brain barrier

by University of Southern California New USC research reveals how APOE4, a genetic culprit for Alzheimer’s disease, triggers leaks in the brain’s plumbing system, allowing toxic substances to seep into the brain areas responsible for memory encoding and other cognitive functions. The damage is linked to future problems in learning and memory, even when the...

Alzheimer’s patients may need dosing changes in medicines prescribed for other conditions
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Alzheimer’s patients may need dosing changes in medicines prescribed for other conditions

by American Chemical Society Patients with Alzheimer’s disease (AD) are often prescribed drugs for other conditions—including diabetes or high blood pressure—at the same doses as those without dementia. That practice might need to be reexamined in the wake of new mouse studies reported in ACS’ Molecular Pharmaceutics. The findings suggest that AD could alter absorption...

Our own immune cells damage the integrity of the blood-brain barrier
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Our own immune cells damage the integrity of the blood-brain barrier

by Nagoya University Researchers have shown that microglia, a class of immune cells in the brain, regulate the permeability of the brain’s protective barrier in response to systemic inflammation. During inflammation, microglia initially protect the barrier’s integrity, but they can later reverse their behavior and increase the barrier’s permeability. The blood-brain barrier is a layer...

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Treatment for depression must also restore proper functioning of the blood-brain barrier

by Laval University To better treat people with depression, not only must we treat the neurons affected by the disease, but we must also restore the integrity of the barrier that regulates exchanges between blood circulation and the brain. This is the conclusion of a study published today in PNAS by Université Laval researchers and...