by RCSI Circadian variation in mitochondrial calcium and antigen processing is directed via control of the mitochondrial calcium uniporter. a Spleens were isolated from WT mice at ZT 1, 7, 13 and 19. CD11c+ cells were isolated and mRNA analyszd by qPCR. Circadian analysis was performed using Metacycle and cycMethod set to “JTK”. P value for each gene is specified...
Our body clock allows bodily processes to occur at certain times of the day, like eating, sleeping, and body temperature. But did you know that monitoring a person’s body clock (or circadian rhythm) could help diagnose and treat asthma? New research supported by Asthma UK, a charity which provides health advice and a helpline to...
By LOIS ROGERS FOR THE DAILY MAIL PUBLISHED: 17:31 EDT, 28 June 2021 | UPDATED: 17:31 EDT, 28 June 2021 After a harrowing childhood, a troubled first marriage, and the loss of two of her children, Maz Rhodes suffered for years with depression, as well as insomnia. In fact, the two have strong links — according to one major study...
Multiple sclerosis (MS) is a debilitating demyelinating disease. It happens when the insulating covers of nerve cells in the brain and spinal cord are damaged and signal transmission in the nervous system becomes disrupted. Scientists at the University of Edinburgh found a way how the body could protect itself from the damages of MS. This...
“You know how Carl Sagan said that we have billions of stars? Well, we have billions of clocks,” says Carrie Partch. “Someday I think there’s going to be this palm-to-forehead moment where we all say: I cannot believe we didn’t understand that every form of life on this planet has a clock that links us to...
A new blood test will be able to determine a person’s body clock compared to external time, a breakthrough that may help with personalized medical treatments. The biological clock is officially referred to as circadian rhythms, a burgeoning field of research that looks to determine the clock’s effects on how a person’s body works. Scientists...
The first simple blood test to identify your body’s precise internal time clock as compared to the external time has been developed by Northwestern Medicine scientists. Credit: CC0 Public Domain The test, TimeSignature—which requires only two blood draws—can tell physicians and researchers the time in your body despite the time in the external world. For...
Researchers at RCSI and Trinity College Dublin have revealed insights into how the body clock controls the inflammatory response, which may open up new therapeutic options to treat excess inflammation in conditions such as asthma, arthritis and cardiovascular disease. By understanding how the body clock controls the inflammatory response, we may be able to target these...
Discovery of an anti-aging supplement that reduces jet lag in mice IMAGE: STUDIES SHOW THAT APPROXIMATELY 5 PERCENT OF THE EXISTING DRUGS MAY HAVE AN EFFECT ON CIRCADIAN RHYTHMS. Using drug repurposing, a team of researchers led by animal biologists at Nagoya University has discovered compounds that can either shorten or lengthen the circadian rhythm in...
For people who don’t get sleepy until 2 a.m., the buzz of an alarm clock can feel mighty oppressive. Relief may be on the horizon, thanks to the discovery this spring of a genetic mutation that causes night-owl behavior. Whether you’re a night owl or a morning lark rising effortlessly each day with the sun, your...
